99608-22-7 Usage
Uses
Used in Research Settings:
(2-iodovinyl)-19-nortestosterone is used as a research compound for investigating its potential as a performance-enhancing drug and exploring its effects on muscle growth, strength, and recovery. Its high potency and anabolic properties make it a subject of interest for scientific studies.
Used in Hormone Replacement Therapy Research:
In addition to its athletic applications, (2-iodovinyl)-19-nortestosterone is also used as a research substance for hormone replacement therapy. Its androgenic effects may have potential benefits for conditions that require hormone supplementation, although further research is necessary to determine its safety and efficacy in this context.
Used in Drug Development:
The unique properties of (2-iodovinyl)-19-nortestosterone make it a candidate for drug development, particularly in the area of hormone-related therapies. Researchers may use (2-iodovinyl)-19-nortestosterone as a starting point to develop new medications with improved safety profiles and targeted effects.
Check Digit Verification of cas no
The CAS Registry Mumber 99608-22-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,6,0 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 99608-22:
(7*9)+(6*9)+(5*6)+(4*0)+(3*8)+(2*2)+(1*2)=177
177 % 10 = 7
So 99608-22-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H27IO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h10-12,15-18,23H,2-9H2,1H3/b11-10+/t15-,16?,17+,18-,19-,20+/m0/s1/i21-2
99608-22-7Relevant academic research and scientific papers
A facile and improved synthesis of 17α-{2-(E)-[125I]-iodovinyl}-19-nortestosterone, a no-carrier-added ligand for progesterone receptor analyses
Damodaran,Epperly,Pillai,Bloomer
, p. 17 - 26 (2007/10/02)
Strategies for human breast cancer therapy using 125I-labeled steroid hormones are clinically attractive in light of the estrogen dependence of and progestogen receptor involvement in many cancers and the favorable microdosimetry resulting from 125I decay. We have synthesized the no-carrier-added progesterone receptor ligand 17α-{2-(E)-[125I]-iodovinyl}-19-nortestosterone (E-125IVNNT) by a simple and high yielding method, and determined its uptake and specific progesterone receptor binding in vitro using T47D human breast carcinoma cells. The ligand was prepared by [125I]-iododestannylation of 17α-[2-(E)-tri-n-butylstannylvinyl]-19-nortestosterone (E-TBSVNNT) by using the rare iodinating agent [125I]-sodium iodide/ferric sulfate in mixed dichloromethane-water solvent. Cell binding assays demonstrated that E-125IVNNT binding to T47D breast carcinoma was specific and saturable with an affinity for the progesterone receptor 10-fold greater than that of 3H-R5020.
