99618-04-9Relevant academic research and scientific papers
Synthesis and evaluation of 2-aryl-1H-benzo[d]imidazole derivatives as potential microtubule targeting agents
Lee, Jung-Seop,Nimse, Satish Balasaheb,Shinde, Pramod B.,Song, In-ho,Song, Keum-soo,Warkad, Shrikant Dashrath,Yeom, Gyu Seong
, (2022/01/20)
Microtubule targeting agents (MTAs) are the potential drug candidates for anticancer drug discovery. Disrupting the microtubule formation or inhibiting the de-polymerization process by a synthetic molecule can lead to an excellent anticancer drug candidat
Three-Way Chemoselectivity Switching through Coupled Equilibria
Puangsamlee, Thamon,Miljani?, Ognjen ?.
supporting information, p. 5900 - 5904 (2020/08/05)
Controlling the chemoselectivity of reactions operating on complex mixtures, including those found in biological and petrochemical feedstocks or in the primordial soup from which life emerged, is generally challenging. The selectivity of imine oxidation c
Chemoselective aerobic oxidation of 2-amino-N-benzylanilines into N-(2-aminophenyl)imines via a nitroxide-free copper catalysis
Zhai, Yadong,Rong, Jing,Zhang, Zhicheng,Cao, Xiang,Su, Zhenni,Zhou, Qingfa,Tao, Chuanzhou
, p. 1139 - 1142 (2019/03/21)
Chemoselective oxidative synthesis of N-(2-aminophenyl)imines from 2-amino-N-benzylanilines was accomplished through combined use of O2(air) and copper salt. This transformation was performed at room temperature, and the mild oxidation was efficient and chemoselective without using nitroxyl radicals and ligands.
Synthesis of 2-aminoquinoxalines via one-pot cyanide-based sequential reaction under aerobic oxidation conditions
Cho, Yeon-Ho,Kim, Kyung-Hee,Cheon, Cheol-Hong
, p. 901 - 907 (2014/03/21)
A highly efficient synthesis of 2-aminoquinoxalines has been developed via the one-pot two-step cyanide-mediated sequential reactions of ortho-phenylenediamines with aldehydes under aerobic oxidation conditions. A variety of substrates, including aliphati
AN EXPEDIENT ROUTE TO 1H-BENZIMIDAZOLES AND 1H-IMIDAZOPYRIDINES
Eynde, Jean-Jacques Vanden,Mayence, Annie,Maquestiau, Andre,Anders, Ernst
, p. 357 - 364 (2007/10/02)
1H-Benzimidazoles, 1H-imidazopyridines, and 1H-imidazopyridines can be synthesized readily by reaction of unisolated N-(1-chloroalkyl)pyridinium chlorides with 1,2-benzenediamines, 2,3-pyridinediamine, and 3,4-pyridinediamine, respectively.
