99619-30-4Relevant academic research and scientific papers
Synthesis of 2,3-Disubstituted Indoles via Claisen Ortho Ester Rearrangement: An Approach for the Synthesis of Vindrosine
Raucher, Stanley,Klein, Peter
, p. 123 - 130 (1986)
The preparation of 10, a potentially useful synthon for the construction of the E ring of vindoline (3) and vindrosine (4), is detailed.The 2,3-disubstituted indoles 5 were prepared via Claisen ortho ester rearrangement of 15 with trimethyl orthoacetate,
