99642-17-8

Usage

Uses

Used in Psychotherapy:
MDMAM is utilized as a therapeutic agent for enhancing empathogenic and entactogenic effects during psychotherapy sessions. Its ability to foster feelings of empathy, emotional closeness, and interpersonal communication makes it a promising candidate for the treatment of various mental health conditions, particularly those that benefit from improved social and emotional connections.
Used in Research:
In the scientific community, MDMAM serves as a research chemical, aiding in the investigation of the neurological and psychological effects of psychoactive substances. Its structural and functional similarities to MDMA allow researchers to explore the mechanisms underlying their effects and potentially develop safer or more effective therapeutic agents.
Used in Pharmaceutical Development:
MDMAM is also employed in the development of new pharmaceuticals, as its unique properties may contribute to the creation of novel treatments for various conditions. The study of MDMAM can provide insights into the design of drugs with targeted effects on specific aspects of emotional and social cognition.
Used in Forensic Toxicology:
In forensic toxicology, MDMAM is used as a reference compound for the identification and analysis of substances in biological samples. Its presence in samples can be indicative of drug use or abuse, and understanding its chemical properties aids in the accurate detection and quantification of related substances.

Upstream product

• 121-90-4 m-nitrobenzoic acid chloride 
• 91-16-7 1,2-dimethoxybenzene 
• 99-05-8 meta-aminobenzoic acid 
• 108620-68-4 3,4-dimethoxy-3'-nitro-benzophenone 

Downstream Products

• 102446-51-5 morpholino-acetic acid-(3-veratroyl-anilide) 
• 71969-32-9 (4-aminophenyl)(3,4-dimethoxyphenyl)methanone 
• 112325-70-9 morpholino-acetic acid-(3-veratryl-anilide) 
• 99642-01-0 C₁₇H₂₁N₃O₅S 

Relevant academic research and scientific papers

Efficient one-pot Friedel-Crafts acylation of benzene and its derivatives with unprotected aminocarboxylic acids in polyphosphoric acid

A number of aminobenzophenones have been synthesized by acylation of benzene and its derivatives with different 2-,3-,4-aminobenzoic and 4-aminophenyl-acetic acids in polyphosphoric acid via Friedel-Crafts reaction as compounds with expected antitumor activity. Copyright Taylor & Francis Group, LLC.

Immunotherapeutic agents

Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor α, nuclear factor κB, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3,3-bis-(3,4-dimethoxyphenyl)acrylonitrile.

Utility of Complementary Molecular Reactivity and Molecular Recognition (CMR/R) Technology and Polymer-Supported Reagents in the Solution-Phase Synthesis of Heterocyclic Carboxamides

The use of our recently reported chemical library purification strategy in the development of a herbicidal lead, N-(3-benzoylphenyl)-3-(1,1-dimethylethyl)-1-methyl-1H-pyrazole-5-carboxamide (3), is described. The approach applying fundamental properties of complementary molecular reactivity and molecular recognition (CMR/R) as the basis for a general purification strategy was utilized. Polymeric reagents were used in the synthesis to generate reactive species involved in product formation, and complementary molecular reactivity/molecular recognition polymer 8 (CMR/R polymer 8) was used in the solution-phase syntheses of building blocks, primary libraries, and lead refinement libraries. An extension of the CMR/R methodology was applied, utilizing a sequestration enabling reagent (SER), transforming a reactant into an electrophilic species sequestrable by CMR/R polymer 8. This library purification strategy enabled rapid lead generation and lead refinement to afford herbicide 27o. The CMR/R solid-phase purification technique enabled a simple, general, and powerful protocol, eliminating the usual tedious and time-consuming methods required for solution-phase product purification. The result was the synthesis of hundreds of compounds, prepared in a relatively short time, leading to a compound with a 4-fold improvement in herbicidal activity over the initial lead.