99654-71-4Relevant academic research and scientific papers
Tricarbonylchromium Complexes of Aryltrimethylsilanes - Synthesis and Reactions
Effenberger, Franz,Schoellkopf, Klaus
, p. 4356 - 4376 (2007/10/02)
Tricarbonylchromium (TCC) complexes 3, 12 of aryltrimethylsilanes are synthesized by reaction of aryltrimethylsilanes 2 and phenylenebis(trimethylsilanes) 11, resp., with hexacarbonylchrom (1).Under basic catalysis 3 and 12 react - caused by the acceptor effect of the tricarbonylchromium (TCC) group - with aldehydes and ketones to give the TCC-alkyl(trimethylsilyl) ether complexes 4, 9, 13.Hydrolysis of 4, 13 accomplish TCC complexes 5 of substituted benzyl alcohols.The oxidative removal of the TCC group with iodine or sodium dichromate was demonstrated with 4a yieldi ng benzhydrol (7) and benzophenone (8f), respectively.Nucleophiles can be added to the aromatic ring of 4, 9, 13 by known methods; the TCC complexes 3, 12, therefore, can be used for the straightforward synthesis of multiply substituted arenes by combination of electrophilic carbodesilylation and nucleophilic addition.
