99705-29-0Relevant academic research and scientific papers
Incorporation of two molecules of carbon monoxide into N-lithioketimine leading to azetidine-2,3-diones
Kai, Hidetomo,Orita, Akihiro,Murai, Shinji
, p. 1989 - 2000 (1998)
The reaction of N-lithioketimines 1, prepared in situ from R1CN (R1 = t-Bu, 1-adamantyl, CH3OCH2(CH3)2C) and R2Li (R2 = t-Bu, s-Bu), with CO followed by addition of MeI affords azetidine-2,3-diones 2 in 40-86% yields. The reaction involves incorporation of two molecules of CO into the N- lithioketimine.
NOVEL IMIDAZO BASED HETEROCYCLES
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Page/Page column 49-50, (2010/11/26)
The present invention is directed to novel imidazopyrazine and imidazopyrimidine compounds of formula (I), wherein the variables are as defined herein. The compounds of formula (I) are useful as kinase inhibitors and as such would be useful in treating ce
1-BENZYLINDOLE-2-CARBOXAMIDE DERIVATIVES
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Page/Page column 53, (2010/11/24)
The present invention relates to i-benzylindole-2-carboxamide derivatives of formula I, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 1-benzylindole-2-carboxamide deriva
Simultaneous preparation of nitriles and acrylamide or methacrylamide
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, (2008/06/13)
Nitriles of the general formula I where R1 is a saturated or unsaturated, straight-chain, branched or cyclic alkyl radical, an aralkyl radical or an aryl radical, each of which is of not more than 20 carbon atoms and can be unsubstituted or further substituted, and (meth)acrylamide are prepared simultaneously by a process in which an aldoxime of the general formula III where R1 has the above meanings, is heated at from 50° to 180° C. in the presence of a copper(II) carboxylate and of (meth)acrylonitrile.
