99706-44-2

Basic information

• Product Name: bis(2-hydroxy-4-methylphenyl)phosphinic acid
• CAS NO: 99706-44-2
• Molecular Weight: 278.244
• Mol File: 99706-44-2.mol

Chemical Properties

• CAS DataBase Reference: bis(2-hydroxy-4-methylphenyl)phosphinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: bis(2-hydroxy-4-methylphenyl)phosphinic acid(99706-44-2)
• EPA Substance Registry System: bis(2-hydroxy-4-methylphenyl)phosphinic acid(99706-44-2)

Safety Data

• Hazardous Substances Data: 99706-44-2(Hazardous Substances Data)

Upstream product

• 99706-40-8 ethyl bis(2-hydroxy-4-methylphenyl)phosphinate 

Relevant articles and documents

Metalation-Induced Double Migration of Phosphorus from O-->C. Convenient Preparation of Bis(2-hydroxyaryl)phosphinic Acids

Treatment of diaryl ethyl phosphates 8 with lithium diisopropylamide in tetrahydrofuran yields ethyl bis(2-hydroxyaryl)phosphinates 9.The reaction involves the double migration of phophorus from O-->C and is probably intramolecular.These phosphinate esters 9 on treatment with trimethylsilyl chloride and sodium iodide in acetonitrile undergo transesterification to give trimethylsilyl esters that yield the corresponding phosphinic acids 15 on treatment with water.