99733-97-8

Upstream product

• 57291-29-9 3-methyl-5-(2′,6′,6′-trimethylcyclohex-1′-enyl)-1-penten-3-ol 
• 593-60-2 Vinyl bromide 
• 17283-81-7 4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on 
• 1826-67-1 vinyl magnesium bromide 

Downstream Products

• 108893-76-1 cis-β-Monocyclofarnesylacetic acid 
• 108893-75-0 trans-β-Monocyclofarnesylacetic acid 
• 173323-70-1 (Z)-β-monocyclohomofarnesylic acid dimethyl amide 
• 173323-69-8 (E)-β-monocyclohomofarnesylic acid dimethyl amide 
• 1040738-26-8 C₂₀H₂₈FNO 
• 468-84-8 (+/-)-(4aR,6aS,10aS,10bS)-4a,7,7,10a-tetramethyldodecahydrobenzo[f]chromen-3-one 
• 3738-00-9 (3aRS,5aSR,9aSR,9bSR)-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 
• 3738-00-9 (±)-ambrox 
• 110202-07-8 (E)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol 
• 110202-08-9 (Z)-4-Methyl-6-(2',6',6'-trimethyl-1'-cyclohexenyl)hex-3-en-1-ol 
• 3738-00-9 (3aRS,5aRS,9aRS,9bSR)-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 

Relevant academic research and scientific papers

Breaking the dichotomy of reactivity vs. chemoselectivity in catalytic SN1 reactions of alcohols

The inability to decouple Lewis acid catalysis from undesirable Bronsted acid catalysed side reactions when water or other protic functional groups are necessarily present has forced chemists to choose between powerful but harsh catalysts or poor but mild

PROCESS FOR PRODUCTION OF (±)-3a,6,6,9a TETRAMETHYLDECAHYDRONAPHTHO[2,1-b]FURAN-2(1H)-ONE

The present invention relates to industrially useful production processes in which (±)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(1H)-ones and further (±)-3a,6,6,9a-tetramethyldo decahydronapbtho[2,1-b]furans are produced from raw materials which are readily available at low costs, through short steps and in a simple manner. The process for producing (±)-3a,6,6,9a-tetramethyldecahydronaphtho[2,1-b]furan-2(1H)-ones represented by the general formula (III): which includes the steps of cyclizing a homofarnesylic acid amide represented by the general formula (I): wherein R1 and R2 are each independently an alkyl group having 1 to 4 carbon atoms; and wavy lines each represents a carbon-to-carbon single bond having a cis or trans structure, and/or a monocyclohomofarnesylic acid amide represented by the general formula (II): wherein R1 and R2 and wavy lines are the same as defined above; and dotted lines represent that a carbon-to-carbon double bond is present at any of positions represented by the dotted lines, in the presence off an acid agent; and subjecting the cyclized product to hydrolysis.

Allylic alcohols as radical allylating agents. An overall olefination of aldehydes and ketones

2-Fluoropyridyl derivatives of allylic alcohols react with xanthates in the presence of lauroyl peroxide to give alkenes, often with high stereoselectivity. If the allylic alcohols are themselves derived from aldehydes or ketones, the overall process becomes a synthetic equivalent of the classical Wittig and related olefination reactions. Copyright

New Syntheses of (+/-)-Ambrox, (+/-)-Ambra Oxide and Their Stereoisomers

New and efficient syntheses of (+/-)-ambrox (1a), (+/-)-ambra oxide (2a) and their stereoisomers (1b, 2b ca. c), amber-like odorous compounds, are described.Starting from dihydro β- and α-ionone (5,12), these substances were obtained in only a few steps via stereoselective acid-catalized cyclization of monocyclodienoic acid (7a ca. b, 11a ca. b, 15a).