99746-86-8

Upstream product

• 108-98-5 thiophenol 
• 90497-62-4 (4S)-4-phenylthio-2-azetidinone 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 90497-66-8 [(3R,4S)-1-(tert-Butyl-dimethyl-silanyl)-2-oxo-4-phenylsulfanyl-azetidin-3-yl]-carbamic acid benzyl ester 
• 90497-65-7 (3R,4S)-3-Amino-1-(tert-butyl-dimethyl-silanyl)-4-phenylsulfanyl-azetidin-2-one 
• 90497-67-9 ((2S,3R)-2-Benzenesulfonyl-4-oxo-azetidin-3-yl)-carbamic acid benzyl ester 
• 99705-36-9 ((3R,4S)-2-Oxo-4-phenylsulfanyl-azetidin-3-yl)-carbamic acid benzyl ester 
• 90497-64-6 (3R,4S)-3-Azido-1-(tert-butyl-dimethyl-silanyl)-4-phenylsulfanyl-azetidin-2-one 

Relevant academic research and scientific papers

The efficient synthesis of chiral key intermediates for monobactam antibiotics

Chemical asymmetric syntheses of the key intermediates (4,6,8) for the synthesis of monobactam antibiotics (SQ 26776 (azthreonam, sulfazecin, and SQ 26180) are accomplished from (±)-4-phenylsulfonyl-2-azetidinone.