99747-46-3Relevant academic research and scientific papers
Regioselective Addition of Butenyl Grignard Reagent to the Unactivated Double Bond of 2-(α-Methylallyl) Aza Aromatic Compounds
Lazzaroni, Raffaello,Pini, Dario,Bertozzi, Sergio,Fatti, Graziella
, p. 505 - 507 (2007/10/02)
The addition of the butenyl Grignard reagent to the unactivated double bond of 2-(α-methylallylic) aza aromatic compounds is completely regioselective giving the 2-(1,4-dimethyl-5 hexen-1-yl) aza aromatics in good yield.A preliminary coordination of magnesium atom to nitrogen atom and the formation of a six-center transition state involving the butenyl Grignard and the vinyl group has been proposed in order to explain the selectivity of the reaction.
