99777-81-8 Usage
General Description
Troxipide is a well-tolerated and effective nonsteroidal anti-inflammatory drug (NSAID) that belongs to the family of pyridinone derivatives. It is commonly used to treat a variety of gastrointestinal disorders, suchjson as gastric ulcers, gastritis, and gastrointestinal reflux disease (GERD). Troxipide works by inhibiting the production of pro-inflammatory mediators, such as leukotrienes and prostaglandins, and by protecting the gastric mucosa from damage caused by acidic and oxidative stress. Clinical studies have shown that troxipide is safe and well-tolerated with minimal side effects, making it a popular choice for the treatment of gastrointestinal conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 99777-81-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,7,7 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 99777-81:
(7*9)+(6*9)+(5*7)+(4*7)+(3*7)+(2*8)+(1*1)=218
218 % 10 = 8
So 99777-81-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2O4/c1-19-12-7-10(8-13(20-2)14(12)21-3)15(18)17-11-5-4-6-16-9-11/h7-8,11,16H,4-6,9H2,1-3H3,(H,17,18)
99777-81-8Relevant articles and documents
Troxipide preparation method
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, (2019/02/27)
The invention belongs to the field of pharmaceutical chemical synthesis and relates to a troxipide preparation method. The preparation method includes steps: 1) preparing 3,4,5-triethoxy benzoyl chloride from 3,4,5-trimethoxybenzoic acid and triphosgene in an organic solvent under the catalytic action of an amine catalyst, subjecting to condensation reaction with 3-aminopyridine in an organic solvent in existence of inorganic base, and performing aftertreatment to obtain 3,4,5-triethoxy-N-3-pyridylbenzamide; 2) subjecting the 3,4,5-triethoxy-N-3-pyridylbenzamide to catalytic hydrogenation to obtain a crude product of troxipide, and refining to obtain troxipide. The troxipide preparation method has advantages of easiness in raw material acquisition, short reaction steps, mild conditions, simplicity in aftertreatment, high product quality, high purity and suitableness for industrial production.
