99780-97-9

Basic information

• Product Name: 3-BOC-AMINO-PYRROLIDIN-2-ONE
• Synonyms: 3-BOC-AMINO-PYRROLIDIN-2-ONE;Carbamic acid, N-(2-oxo-3-pyrrolidinyl)-, 1,1-dimethylethyl ester;tert-Butyl (2-oxopyrrolidin-3-yl);tert-butyl N-(2-oxopyrrolidin-3-yl)carbamate
• CAS NO: 99780-97-9
• Molecular Formula: C₉H₁₆N₂O₃
• Molecular Weight: 200.24
• Mol File: 99780-97-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 394.0±31.0 °C(Predicted)
• Appearance: /
• Density: 1.13±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.05±0.20(Predicted)
• CAS DataBase Reference: 3-BOC-AMINO-PYRROLIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BOC-AMINO-PYRROLIDIN-2-ONE(99780-97-9)
• EPA Substance Registry System: 3-BOC-AMINO-PYRROLIDIN-2-ONE(99780-97-9)

Safety Data

• Hazardous Substances Data: 99780-97-9(Hazardous Substances Data)

Usage

General Description

3-BOC-AMINO-PYRROLIDIN-2-ONE, also known as tert-butoxycarbonyl-amino-pyrrolidin-2-one, is a chemical compound commonly used in organic synthesis and medicinal chemistry. It is a derivative of pyrrolidin-2-one and features a BOC (tert-butoxycarbonyl) protecting group attached to the amino group. 3-BOC-AMINO-PYRROLIDIN-2-ONE is often used as a building block for the synthesis of pharmaceuticals, agrochemicals, and other biologically active molecules. Additionally, it can also be used as a reagent for the modification of proteins and peptides. 3-BOC-AMINO-PYRROLIDIN-2-ONE is a versatile and important intermediate in the production of many valuable chemical products.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 2483-65-0 3-amino-pyrrolidin-2-one 

Downstream Products

• 861104-96-3 (1-benzhydryl-2-oxo-pyrrollidin-3-yl)-carbamic acid tert-butyl ester 
• 99707-37-6 1-<(benzyloxycarbonyl)methyl>-3-<(tert-butoxycarbonyl)amino>-2-pyrrolidone 
• 1471471-41-6 methanesulfonic Acid 4-Bromo-3-(3-tert-butoxycarbonylamino-2-oxopyrrolidin-1-ylmethyl)phenyl Ester 

Relevant articles and documents

PHENYLPYRROLIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS

The disclosure relates to compounds of Formulae (I)-(IX), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.

N-type calcium channel blockers

The invention relates to novel 3-amino pyrrolidine derivatives, as well as methods for modulating calcium channel activity and for treating conditions associated with calcium channel function. In particular, the compounds generally contain at least one be

Conformationally Restricted Inhibitors of Angiotensin Converting Enzyme: Synthesis and Computations

A series of inhibitors of angiotensin converting enzyme (ACE, dipeptidyl carboxypeptidase, EC 3.4.15.1) is described which addresses certain conformational aspects of the enzyme-inhibitor interaction.In this study the alanylproline portion of the potent A