99795-88-7

Upstream product

• 99140-54-2 2-(3-Benzyloxy-phenylamino)-6-chloro-3-nitro-benzoic acid 
• 55775-97-8 2,6-dichloro-3-nitrobenzoic acid 
• 1484-26-0 3-(benzyloxy)aniline 
• 6373-46-2 p-benzyloxyaniline 
• 99009-51-5 2-Chloro-5-nitro-6-[[4-(phenylmethoxy)phenyl]amino]benzoic acid 

Downstream Products

• 144346-99-6 [2-(8-Benzyloxy-5-nitro-6H-pyrazolo[3,4,5-kl]acridin-2-yl)-ethyl]-diethyl-amine 
• 99009-26-4 2,2-Dimethyl-propionic acid 2-(3-dimethylamino-propyl)-5-nitro-2,6-dihydro-pyrazolo[3,4,5-kl]acridin-9-yl ester 
• 99009-18-4 9-Desmethylpyrazoloacridine 

Relevant academic research and scientific papers

2-(Aminoalkyl)-5-nitropyrazoloacridines, a New Class of Anticancer Agents

2-(Aminoalkyl)-5-nitropyrazoloacridines were prepared from substituted anilines via the 1-chloro-4-nitroacridones followed by condensation with hydrazines.Impressive activity was demonstrated for the 9-hydroxy, 9-alkoxy, and 9-acyloxy analogs in vitro on a L1210 leukemia line and in vivo against the P388 leukemia.Advanced studies led to the selection of 3bbb for clinical trial.