99838-70-7

Upstream product

• 99838-68-3 (2R,3S)-3-(benzyloxy)hex-5-ene-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 164145-69-1 1(S)-[(2R)-1,4-dioxaspiro[4.5]decanyl]-3-buten-1-ol 
• 942137-19-1 (2R)-2-[(1S)-1-(benzyloxy)-3-butenyl]-1,4-dioxaspiro[4.5]decane 
• 99838-68-3 (2R)-3-benzyloxy-5-hexen-1,2-diol 

Downstream Products

• 942137-20-4 (R)-2-[(S)-1-(benzyloxy)but-3-enyl]oxirane 
• 99838-73-0 (2R,3R)-3-benzyloxy-1,2-epoxy-5-hexene 
• 1447922-67-9 (2R,3S)-3-(benzyloxy)hex-5-en-2-ol 

Relevant academic research and scientific papers

An Enantioselective Synthesis of (5 S,6 R,11 S,14 R)-Acremodiol

An expeditious synthesis of the (5 S,6 R,11 S,14 R)-isomer of acremodiol was developed via a convergent route. One of the required building blocks was synthesized earlier via two sequential lipase-catalyzed secondary carbinol acetylations. The other unit

Synthesis of a hydroxyethylene dipeptide isostere, a core unit of the HIV protease inhibitors ritonavir and lopinavir, and its C-5 epimer

A short synthesis of a hydroxyethylene dipeptide isostere, a core unit of the HIV protease inhibitors ritonavir and lopinavir, and its C-5 epimer is described. Georg Thieme Verlag Stuttgart.

Enantio- and Diastereocontrolled Synthesis of Chiral 1,2-Diol Derivatives from (R)-2,3-Di-O-isopropylideneglyceraldehyde: endo- and exo-Brevicomin

All four possible stereoisomers of the insect pheromone brevicomin have been prepared from (R)-2,3-di-O-isopropylideneglyceraldehyde (1) on stereocontrolled routes with ee more than 98-99percent.