99853-52-8

Usage

Structure

Pyrazole derivative with a chlorine-methyl group and a methyl-phenyl group attached to the pyrazole ring

Usage

Synthesis of various pharmaceuticals and organic compounds, potential applications in the field of medicine, development of new chemical compounds, and research and development in other industries such as agriculture and materials science.

Upstream product

• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 50-00-0 formaldehyd 

Downstream Products

• 875657-57-1 (3-methyl-1-phenyl-1H-pyrazol-4-yl)acetonitrile 

Relevant academic research and scientific papers

PYRAZOLE DERIVATIVES

A compound represented by the general formula (I), which is useful as a peroxisome proliferator-activated receptor α/γ agonist, a salt of the compound, and a solvate of either. (In the formula, X, Y, and Z each represents nitrogen or carbon; m is an integ

An easy method for the N-alkylation of amides, carbamates, ureas and azoles. Reactivity of 4-chloromethylpyrazoles with weak nucleophiles under neutral conditions

4-Chloromethylpyrazoles are shown to react readily with amides, carbamates, ureas and azoles under neutral conditions giving the corresponding N-monoalkylated derivatives with moderate yields. Alkylation of alcohols and thiols occurs under the same conditions. The procedure described may provide a convenient and easy method for the introduction of a 4-pyrazolylmethyl group into molecules containing functional groups with weak nucleophilic character.