99865-07-3

Upstream product

• 93553-66-3 1-(benzyloxy)but-3-en-2-ol 
• 1826-67-1 vinyl magnesium bromide 
• 104863-68-5 2-(benzyloxy)-N-methoxy-N-methylacetamide 
• 19810-31-2 Benzyloxyacetyl chloride 
• 68972-96-3 (Z)-1,4-dibenzyloxy-2-butene 
• 30379-55-6 benzyloxyacetic acid 
• 60656-87-3 benzyloxyacetoaldehyde 
• 100-44-7 benzyl chloride 

Downstream Products

• 132179-97-6 2-(2-(Benzyloxy)-1-oxoethyl)-5-methyl-1-(triisopropylsiloxy)bicyclo<2.2.2>oct-5-ene 
• 132179-97-6 2-(2-(Benzyloxy)-1-oxoethyl)-5-methyl-1-(triisopropylsiloxy)bicyclo<2.2.2>oct-5-ene 
• 946163-72-0 (2S,4R)-benzyl 4-(benzyloxy)-2((E)-4-(benzyloxy)-3-oxobut-1-enyl)pyrrolidine-1-carboxylate 
• 946163-73-1 (2S,4R)-benzyl 4-(benzyloxy)-2((1R,2S)-4-(benzyloxy)-1,2-dihydroxy-3-oxobutyl)pyrrolidine-1-carboxylate 
• 946163-74-2 (2S,4R)-benzyl 4-(benzyloxy)-2((1S,2R)-4-(benzyloxy)-1,2-dihydroxy-3-oxobutyl)pyrrolidine-1-carboxylate 
• 848413-74-1 2-benzyloxy-1-(1-benzyl-pyrrolidin-3-yl)-ethanone 

Relevant academic research and scientific papers

Preparation method of 1-benzyl-8-tert-butyl-2-(hydroxymethyl)-diazaspirane decane dicarboxylate

The invention relates to a preparation method of 1-benzyl-8-tert-butyl-2-hydroxymethyl-1,8-diazaspirane[4.5]decane-1,8-dicarboxylate, mainly aiming at solving the technical problem that a suitable industrial synthesis method does not exist at present. The

L-Selectride-mediated highly diastereoselective asymmetric reductive Aldol reaction: Access to an important subunit for bioactive molecules

(Equation Presented) L-Selectride reduction of a chiral or achiral enone followed by reaction of the resulting enolate with optically active α-alkoxy aldehydes proceeded with excellent diastereoselectivity. The resulting α,α-dimethyl-β-hydroxy ketones are

Synthesis of (+)-7a-epi-7-deoxycasuarine via cross metathesis

Olefin cross metathesis of vinyl pyrrolidine derivatives has been explored, culminating in a concise synthesis of (+)-7a-epi-7-deoxycasuarine in nine steps, from commercially available starting materials.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula (I) as well as pharmaceutically acceptable compositions comprising compounds of formula (I). Compounds of formula (I) as disclosed herein can be used in a variety of applications including use as antibacterial agents.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.

Tandem cycloaddition chemistry of nitroalkenes: Preparative and theoretical studies on the stereochemical course of [3 + 2] cycloaddition of cyclic nitronates

Intermolecular [3 + 2] cycloadditions between two cyclic nitronates and a series of dipolarophiles are examined. High facial selectivity is observed in all cases and is analyzed with the aid of ab initio transition structure calculations. Monosubstituted dipolarophiles reacted with exclusive regiocontrol. Disubstituted dipolarophiles reacted with varying degrees of regiocontrol, which was dependent on the substituent. A theoretical approach for predicting regioselectivity is discussed. Exo selectivity was generally favored due to steric effects, and was especially high with cis-disubstituted dipolarophiles.