99892-63-4Relevant academic research and scientific papers
Acridinium compounds and conjugates thereof
-
, (2008/06/13)
Acridinium compounds represented by the general formula (I) where A is an intervening group which does not have activity for binding with a specific binding substance, Z is a labelling active group which has activity for binding with a specific binding substance, R1 is a halogen atom, an alkyl group or an aryl group; R2, R3, R4 and R5 are each a hydrogen atom, an alkyl group, an aryl group, an alkoxy group, a nitro group, a halogen atom or a carbonyl group, and Y is a counter ion. The acridinium compounds may form conjugates with specific binding substances. The acridinium compounds have high emission efficiency and stability and, hence, are useful as chemiluminescence labelling agents.
BASENINDUZIERTE UMLAGERUNGEN VON 3,9 DIOXATRICYCLO2,4>NONAN-7-ONEN ZU m-HYDROXYPHENYLCARBONYL-VERBINDUNGEN
Foehlisch, Baldur,Herrscher, Otto
, p. 1979 - 1984 (2007/10/02)
8-Oxabicyclooct-6-en-3-ones (5), easily available by cycloaddition, were epoxidised at the C=C double bond.The 3,9-dioxatricyclo2,4>nonan-7-ones (6) thus obtained are rearranged on treatment with sodium ethoxide in ethanol to form 3-hydroxybenzaldehydes (8a-d) and 3-hydroxy-2,4,5-trimethylacetophenone (8e) in good yields.As intermediates of these rearrangements, 8-hydroxy-6-oxatricyclo2,7>octan-3-ones are postulated; the trimethyl derivative 7g and the 6-carba-derivatives 4a,b could be isolated.
