99902-04-2Relevant academic research and scientific papers
A new synthetic approach to 6-unsubstituted phenanthridine and phenanthridine-like compounds under mild and metal-free conditions
Tummatorn, Jumreang,Krajangsri, Suppachai,Norseeda, Krissada,Thongsornkleeb, Charnsak,Ruchirawat, Somsak
supporting information, p. 5077 - 5081 (2014/07/08)
A new and mild synthetic approach for the synthesis of 6-unsubstituted phenanthridine and phenanthridine-like compounds under metal-free conditions at room temperature has been developed. The strategy involved a tandem azide rearrangement/intramolecular annulation and oxidation reactions of biarylmethyl azide precursors to obtain the desired products in up to 99% yields with high regioselectivity.
Inhibition of nucleoside transport by new analogues of 4- nitrobenzylthioinosine: Replacement of the ribose moiety by substituted benzyl groups
Tromp, Reynier A.,Van Ameijde, Susan,Pütz, Claudia,Sundermann, Corinna,Sundermann, Bernd,Von Frijtag Drabbe Künzel, Jacobien K.,Ijzerman, Adriaan P.
, p. 5441 - 5450 (2007/10/03)
4-Nitrobenzylthioinosine (NBTI, 1) is a well-known inhibitor for the nucleoside transport protein ENT1. However, its highly polar nature is unfavorable for oral absorption and/or penetration into the CNS. In the search for compounds with lower polarity th
Iminium Ion Mediated Cyclizations with 4-Aryl-1,4-dihydropyridines. Bridging with Thiophene and Furan
Hartman, George D.,Halczenko, Wasyl,Phillips, Brian T.
, p. 142 - 148 (2007/10/02)
Treatment of -, phenyl-, - and -1,4-dihydropyridines with aluminum chloride afforded products derived from intramolecular trapping of the dihydropyridine/iminium ion by the
