99902-07-5

Basic information

• Product Name: 2-THIOPHEN-2-YL-BENZALDEHYDE
• Synonyms: 2-THIOPHEN-2-YL-BENZALDEHYDE;2-THIEN-2-YLBENZALDEHYDE;2-(2-THIENYL)BENZALDEHYDE;AKOS BAR-0192;2-(Thien-2-yl)benzaldehyde 97%;2-(Thien-2-yl)benzaldehyde97%
• CAS NO: 99902-07-5
• Molecular Formula: C₁₁H₈OS
• Molecular Weight: 188.25
• Product Categories: Aldehydes;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 99902-07-5.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 331 °C at 760 mmHg
• Flash Point: 124.1 °C
• Appearance: /
• Density: 1.207 g/cm³
• Vapor Pressure: 0.000161mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-THIOPHEN-2-YL-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-THIOPHEN-2-YL-BENZALDEHYDE(99902-07-5)
• EPA Substance Registry System: 2-THIOPHEN-2-YL-BENZALDEHYDE(99902-07-5)

Safety Data

• Hazard Codes: Xi
• Statements: 20/22-36/37/38-41
• Safety Statements: 23-26-36-39
• Hazardous Substances Data: 99902-07-5(Hazardous Substances Data)

Usage

General Description

2-Thiophen-2-yl-benzaldehyde is a chemical compound with a somewhat complex molecular structure consisting of interconnected chemical rings. The chemical formula for this compound is C11H8OS, signifying that it has eleven carbon atoms, eight hydrogen atoms, and one sulfur atom. 2-THIOPHEN-2-YL-BENZALDEHYDE is generally utilized as a precursor or an intermediator in chemical reactions or synthesis to create more elaborate chemical structures. Being an aromatic organic compound, it is predominantly used in laboratories or manufacturing facilities that design chemicals for specific purposes. 2-THIOPHEN-2-YL-BENZALDEHYDE is recognized for its relevance in the production of pharmaceuticals, various polymers, dyes, and it may even have potential applications in creating advanced organic electronic devices.

InChI:InChI=1/C11H8OS/c12-8-9-4-1-2-5-10(9)11-6-3-7-13-11/h1-8H

Upstream product

• 1003-09-4 2-bromothiophene 
• 40138-16-7 2-formylbenzene boronic acid 
• 872-31-1 3-Bromothiophene 
• 188290-36-0 thiophene 
• 6165-68-0 thiophene boronic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 15106-95-3 bis(thien-2-yl)zinc 
• 35822-58-3 2-bromobenzaldehyde diethyl acetal 
• 96-43-5 2-thienyl chloride 
• 89-98-5 2-chloro-benzaldehyde 
• 172983-10-7 2-(cyclohepta-2,4,6-trien-1-yl)thiophene 

Downstream Products

• 221230-46-2 2-(2-ethynyl-phenyl)-thiophene 
• 1332500-51-2 4-methyl-N'-(2-(thiophen-2-yl)benzylidene)benzenesulfonohydrazide 
• 473528-04-0 1-(4-fluorophenyl)-8-[[2-(thien-2-yl)phenyl]methyl]-1,3,8-triazaspiro[4.5]decan-4-one 
• 99922-17-5 dimethyl 2,6-dimethyl-4-<2-(3-thienyl)phenyl>-1,4-dihydropyridine-2,6-dicarboxylate 

Relevant articles and documents

Gold Catalysts Can Generate Nitrone Intermediates from a Nitrosoarene/Alkene Mixture, Enabling Two Distinct Catalytic Reactions: A Nitroso-Activated Cycloheptatriene/Benzylidene Rearrangement

Gold-catalyzed reactions of cycloheptatrienes with nitrosoarenes yield nitrone derivatives efficiently. This reaction sequence enables us to develop gold-catalyzed aerobic oxidations of cycloheptatrienes to afford benzaldehyde derivatives using CuCl and nitrosoarenes as co-catalysts (10-30 mol %). Our density functional theory calculations support a novel nitroso-activated rearrangement, tropylium → benzylidene. With the same nitrosoarenes, we developed their gold-catalyzed [2 + 2 + 1]-annulations between nitrosobenzene and two enol ethers to yield 5-alkoxyisoxazolidines using 1,4-cyclohexadienes as hydrogen donors.

Sulphonic acid functionalized porphyrin anchored with a: Meso -substituted triazolium ionic liquid moiety: A heterogeneous photo-catalyst for metal/base free C-C cross-coupling and C-N/C-H activation using aryl chloride under visible light irradiation

We report an easy process to synthesize sulphonic acid functionalized porphyrin, anchored with a meso-substituted triazolium ionic liquid moiety (SAFPTILM) for metal/base free C-C cross-coupling and C-N/C-H activation using aryl chloride under visible light irradiation. The acid strength has been measured based on the Hammett indicator. The SAFPTILM photocatalyst comprising 18 π-conjugated electronic systems with the chromophore substituents in the meso-position can provide rapid electronic conducting channels during photocatalysis under the irradiation of visible light. It was found that SAFPTILM is an efficient photocatalyst for the Heck, Sonogashira, Buchwald, Ullmann/Fittig coupling and C-H activation of phenols with different aryl chlorides in the absence of a base/noble metal, using 5 W LED (yellow) light under ambient conditions. The photocatalyst with low band gap (1.55 eV) comprising conjugation, favors coupling reaction of unactivated aryl chlorides, by easy excitation of electrons and transfer to the conjugated benzimidazolium based phenylenediamine support delaying the recombination of photoinduced electron-hole pairs.

Bench-Stable Sulfoxide-Based Boronates: Preparation and Application in a Tandem Suzuki Reaction

A set of novel aromatic and heteroaromatic bench-stable sulfoxide-based boronates was prepared. The structure of the boronates was established by means of X-ray crystallography, and the prepared boronates were successively used in Suzuki cross-coupling reactions under different conditions. We also developed a tandem Suzuki reaction so that a base is generated during the nucleophilic addition of Grignard reagents to 4-bromobenzaldehyde. The formed intermediates were smoothly coupled with the prepared boronates and the boronic acids under external base-free conditions. (Figure presented.).