99930-89-9

Upstream product

• 61783-64-0 (+)-(S)-1-hexynyl p-tolyl sulfoxide 
• 32359-01-6 hexenylmagnesium bromide 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 647835-10-7 (SS,SS,2R)-1,1-bis-p-tolylsulfinyl-2-methylhexane 
• 693-02-7 hex-1-yne 
• 544-97-8 dimethyl zinc(II) 
• 917-54-4 methyllithium 

Relevant academic research and scientific papers

Diastereoselective synthesis of enantiopure acyclic ss,ss -disubstituted vinylsulfoxides

Thermal elimination of sulfenic acid from enantiopure ss,ss -disubstituted bis-sulfoxides allows the stereoselective synthesis of enantiopure acyclic ss,ss -disubstituted vinylsulfoxides. This mild and stereospecific synthesis provides either (E) or (Z) v

Geometrically selective synthesis of functionalized β,β -disubstituted vinylic sulfoxides by Cu-catalyzed conjugate addition of organozinc reagents to 1-alkynyl sulfoxides

(Matrix presented) A new synthetic method of chiral β,β -disubstituted vinylic sulfoxides bearing various functionalities has been developed by employing Cu-catalyzed conjugate addition of an organozinc reagent to chiral 1-alkynyl sulfoxide. Since the reaction proceeds with very high syn-selectivity, both geometric β,β-disubstituted vinylic sulfoxides were stereoselectively synthesized by changing the combination of 1-alkynyl sulfoxide and the organozinc reagent.

Simple and Stereocontrolled Preparation of Optically Pure (E)- and (Z)-1-Alkenyl p-Tolyl Sulfoxides via 1-Alkynyl p-Tolyl Sulfoxides

1-Alkynylmagnesium bromides react cleanly and stereospecifically with (-)-menthyl (-)-(S)-p-toluenesulfinate (2) in toluene to produce chiral 1-alkynyl p-tolyl (+)-(S)-sulfoxides 5a-d in high yields.Reduction of 5a-d with lithium aluminum hydride in THF a

A SIMPLE PREPARATIVE METHOD FOR OPTICALLY PURE 1-ALKENYL p-TOLYL SULFOXIDES VIA 1-ALKYNYL p-TOLYL SULFOXIDES

1-Alkynyl Grignard reagents react with (SS)-(-)-menthyl p-toluene-sulfinate in toluene to give optically active 1-alkynyl p-tolyl sulfoxides in high yields.The 1-alkynyl sulfoxides thus obtained undergo a stereoselective hydroalumination follow