99979-77-8Relevant articles and documents
Fused pyrimidine ring derivative, preparation method therefor and application thereof
-
Paragraph 0242; 0243; 0244, (2016/10/07)
The invention discloses a type of fused pyrimidine ring derivatives shown in a formula (I) acting as a tyrosine kinase inhibitor and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, A and B are as defined in the description. The inve
FUSED IMIDAZOLE AND PYRAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY
-
Page/Page column 103, (2015/06/25)
A series of substituted benzimidazole, imidazo[1,2-a]pyridine and pyrazolo[1,5-a]pyridine derivatives, and analogues thereof, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES
-
Page/Page column 128, (2010/01/07)
The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.