99985-63-4Relevant academic research and scientific papers
Total synthesis of (±)-symbioimine
Zou, Yefen,Che, Qinglin,Snider, Barry B.
, p. 5605 - 5608 (2007/10/03)
The synthesis of (±)-symbioimine (1) has been completed in only 12 linear steps in 8% overall yield. The key step is the treatment of 13b with BF3·Et2O to generate N-carboalkoxydihydropyridinium cation 14b, which undergoes a novel stereospecific intramole
Synthesis of 2,4-, 3,4- and 2,3,4-substituted pyrrolidines by cyclization of neutral C-centered α-aminoalkyl radicals
Bustos, Fernando,Gorgojo, José M,Suero, Rubén,Aurrecoechea, José M
, p. 6837 - 6842 (2007/10/03)
The effect of substitution at C-3 or C-4 of the 2-azahex-5-enyl chain has been studied in the SmI2-promoted cyclizations of neutral α-aminoalkyl radicals generated from N-(α-benzotriazolyl)alkenylamines. 2,4-, 3,4- and 2,3,4-substituted pyrroli
Quinoline, naphthyridine and pyridobenzoxazine derivatives
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, (2008/06/13)
Novel antibacterial compounds are disclosed having the formula STR1 as well as pharmaceutically acceptable salts, esters, amide and prodrugs thereof, wherein R1 is selected from the group consisting of (a) lower alkyl, (b) halo(lower alkyl), (c
Quinoline-3-carboxylic acid derivatives
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, (2008/06/13)
Compounds of formula (I): STR1 (in which R1 is alkoxy, R is alkyl, haloalkyl, alkylamino, cycloalkyl or optionally substituted phenyl, X is chlorine or fluorine and Y is selected from certain specific heterocycles) have excellent antibacterial activity. They may be prepared by introducing the group represented by Y into the corresponding compound in which Y is replaced by a halogen atom.
Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof
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, (2008/06/13)
Pyridonecarboxylic acid derivatives of the following formula, STR1 wherein R is hydrogen atom or lower alkyl group, R1 is lower alkyl group, cycloalkyl group or haloalkyl group, Y is hydrogen atom or halogen atom, or Y and R1 are STR
