Phenol, 2,2'-thiobis(4,6-dichloro-

CAS  

 97-18-7

SYNONYMS  

 * Actamer
* Bidiphen
* Bis(3,5-dichloro-2-hydroxyphenyl) sulfide
* Bis(2-hydroxy-3,5-dichlorophenyl) sulfide
* Bithionol
* Bitin
* Bitionol
* CP 3438
* D 26
* 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylsulfide
* 2-Hydroxy-3,5-dichlorophenyl sulphide
* Lorothidol
* Lorothiodol
* NCI-C60628
* Neopellis
* Nobacter
* 2,2'-Thiobis(4,6-dichlorophenol)
* TKhsd
* USAF B-22
* Vancide BL
* XL 7

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : SN0525000
CHEMICAL NAME           : Phenol, 2,2'-thiobis(4,6-dichloro-
CAS REGISTRY NUMBER     : 97-18-7
BEILSTEIN REFERENCE NO. : 2003535
REFERENCE               : 4-06-00-05646 (Beilstein Handbook Reference)
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C12-H6-Cl4-O2-S
MOLECULAR WEIGHT        : 356.04
WISWESSER LINE NOTATION : QR BG DG FSR BQ CG EG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * Actamer
   * Bidiphen
   * Bis(3,5-dichloro-2-hydroxyphenyl) sulfide
   * Bis(2-hydroxy-3,5-dichlorophenyl) sulfide
   * Bithionol
   * Bitin
   * Bitionol
   * CP 3438
   * D 26
   * 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenylsulfide
   * 2-Hydroxy-3,5-dichlorophenyl sulphide
   * Lorothidol
   * Lorothiodol
   * NCI-C60628
   * Neopellis
   * Nobacter
   * 2,2'-Thiobis(4,6-dichlorophenol)
   * TKhsd
   * USAF B-22
   * Vancide BL
   * XL 7
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 760 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,612,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#01763
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 gm/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***