|
1.
1.1
IDENTIFICATION
OF
THE
SUBSTANCE/MIXTURE
AND
OF
THE
COMPANY/UNDERTAKING
Product
identifiers
Product
name
Product
Number
Brand
Index-No.
CAS-No.
:
:
:
:
:
Prostaglandin
H2
P7867
606-001-00-8
42935-17-1
1.2
Relevant
identified
uses
of
the
substance
or
mixture
and
uses
advised
against
Identified
uses
:
Laboratory
chemicals,
Manufacture
of
substances 2.
2.1
2.2
HAZARDS
IDENTIFICATION
Classification
of
the
substance
or
mixture
Classification
according
to
Regulation
(EC)
No
1272/2008
[EU-GHS/CLP]
Flammable
liquids
(Category
2)
Eye
irritation
(Category
2)
Specific
target
organ
toxicity
-
single
exposure
(Category
3)
Classification
according
to
EU
Directives
67/548/EEC
or
1999/45/EC
Highly
flammable.
Irritating
to
eyes.
Repeated
exposure
may
cause
skin
dryness
or
cracking.
Vapours
may
cause
drowsiness
and
dizziness.
Label
elements
Labelling
according
Regulation
(EC)
No
1272/2008
[CLP]
Pictogram
Signal
word
Hazard
statement(s)
H225
H319
H336
Precautionary
statement(s)
P210
P261
P305
+
P351
+
P338
Danger
Highly
flammable
liquid
and
vapour.
Causes
serious
eye
irritation.
May
cause
drowsiness
or
dizziness.
Keep
away
from
heat/sparks/open
flames/hot
surfaces.
-
No
smoking.
Avoid
breathing
dust/
fume/
gas/
mist/
vapours/
spray.
IF
IN
EYES:
Rinse
cautiously
with
water
for
several
minutes.
Remove
contact
lenses,
if
present
and
easy
to
do.
Continue
rinsing.
Supplemental
Hazard
information
(EU)
EUH066
Repeated
exposure
may
cause
skin
dryness
or
cracking.
According
to
European
Directive
67/548/EEC
as
amended.
Hazard
symbol(s)
R-phrase(s)
R11
R36
R66
R67
S-phrase(s)
S9
S16
S26
Highly
flammable.
Irritating
to
eyes.
Repeated
exposure
may
cause
skin
dryness
or
cracking.
Vapours
may
cause
drowsiness
and
dizziness.
Keep
container
in
a
well-ventilated
place.
Keep
away
from
sources
of
ignition
-
No
smoking.
In
case
of
contact
with
eyes,
rinse
immediately
with
plenty
of
water
and
seek
medical
advice.
2.3
3.
3.2
Other
hazards
-
none
COMPOSITION/INFORMATION
ON
INGREDIENTS
Mixtures
Synonyms
Formula
Molecular
Weight
:
:
:
PGH2
Endoperoxide
H2
Prostaglandin
R2
C20H32O5
352,47
g/mol
Component
Acetone
Classification
Concentration
CAS-No.
EC-No.
Index-No.
67-64-1
200-662-2
606-001-00-8
Flam.
Liq.
2;
Eye
Irrit.
2;
STOT
50
-
100
%
SE
3;
H225,
H319,
H336,
EUH066
F,
Xi,
R11
-
R36
-
R66
-
R67
For
the
full
text
of
the
H-Statements
and
R-Phrases
mentioned
in
this
Section,
see
Section
16
4.
4.1
4.2
FIRST
AID
MEASURES
Description
of
first
aid
measures
General
advice
Consult
a
physician.
Show
this
safety
data
sheet
to
the
doctor
in
attendance.
If
inhaled
If
breathed
in,
move
person
into
fresh
air.
If
not
breathing,
give
artificial
respiration.
Consult
a
physician.
In
case
of
skin
contact
Wash
off
with
soap
and
plenty
of
water.
Consult
a
physician.
In
case
of
eye
contact
Rinse
thoroughly
with
plenty
of
water
for
at
least
15
minutes
and
consult
a
physician.
If
swallowed
Do
NOT
induce
vomiting.
Never
give
anything
by
mouth
to
an
unconscious
person.
Rinse
mouth
with
water.
Consult
a
physician.
Most
important
symptoms
and
effects,
both
acute
and
delayed
To
the
best
of
our
knowledge,
the
chemical,
physical,
and
toxicological
properties
have
not
been
thoroughly
investigated.
4.3
5.
5.1
5.2
5.3
5.4
6.
6.1
6.2
6.3
6.4
7.
7.1
7.2
7.3
8.
8.1
8.2
Indication
of
any
immediate
medical
attention
and
special
treatment
needed
no
data
available
FIREFIGHTING
MEASURES
Extinguishing
media
Suitable
extinguishing
media
Use
water
spray,
alcohol-resistant
foam,
dry
chemical
or
carbon
dioxide.
Special
hazards
arising
from
the
substance
or
mixture
Carbon
oxides
Advice
for
firefighters
Wear
self
contained
breathing
apparatus
for
fire
fighting
if
necessary.
Further
information
Use
water
spray
to
cool
unopened
containers.
ACCIDENTAL
RELEASE
MEASURES
Personal
precautions,
protective
equipment
and
emergency
procedures
Use
personal
protective
equipment.
Avoid
breathing
vapors,
mist
or
gas.
Ensure
adequate
ventilation.
Remove
all
sources
of
ignition.
Evacuate
personnel
to
safe
areas.
Beware
of
vapours
accumulating
to
form
explosive
concentrations.
Vapours
can
accumulate
in
low
areas.
Environmental
precautions
Prevent
further
leakage
or
spillage
if
safe
to
do
so.
Do
not
let
product
enter
drains.
Methods
and
materials
for
containment
and
cleaning
up
Contain
spillage,
and
then
collect
with
an
electrically
protected
vacuum
cleaner
or
by
wet-brushing
and
place
in
container
for
disposal
according
to
local
regulations
(see
section
13).
Reference
to
other
sections
For
disposal
see
section
13.
HANDLING
AND
STORAGE
Precautions
for
safe
handling
Avoid
contact
with
skin
and
eyes.
Avoid
inhalation
of
vapour
or
mist.
Keep
away
from
sources
of
ignition
-
No
smoking.Take
measures
to
prevent
the
build
up
of
electrostatic
charge.
Conditions
for
safe
storage,
including
any
incompatibilities
Store
in
cool
place.
Keep
container
tightly
closed
in
a
dry
and
well-ventilated
place.
Containers
which
are
opened
must
be
carefully
resealed
and
kept
upright
to
prevent
leakage.
Recommended
storage
temperature:
-70
??C
Specific
end
uses
no
data
available
EXPOSURE
CONTROLS/PERSONAL
PROTECTION
Control
parameters
Components
with
workplace
control
parameters
Exposure
controls
Appropriate
engineering
controls
Handle
in
accordance
with
good
industrial
hygiene
and
safety
practice.
Wash
hands
before
breaks
and
at
the
end
of
workday.
Personal
protective
equipment
Eye/face
protection
Face
shield
and
safety
glasses
Use
equipment
for
eye
protection
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
EN
166(EU).
Skin
protection
Handle
with
gloves.
Gloves
must
be
inspected
prior
to
use.
Use
proper
glove
removal
technique
(without
touching
glove's
outer
surface)
to
avoid
skin
contact
with
this
product.
Dispose
of
contaminated
gloves
after
use
in
accordance
with
applicable
laws
and
good
laboratory
practices.
Wash
and
dry
hands.
The
selected
protective
gloves
have
to
satisfy
the
specifications
of
EU
Directive
89/686/EEC
and
the
standard
EN
374
derived
from
it.
Body
Protection
impervious
clothing,
Flame
retardant
antistatic
protective
clothing,
The
type
of
protective
equipment
must
be
selected
according
to
the
concentration
and
amount
of
the
dangerous
substance
at
the
specific
workplace.
Respiratory
protection
Where
risk
assessment
shows
air-purifying
respirators
are
appropriate
use
a
full-face
respirator
with
multi-purpose
combination
(US)
or
type
ABEK
(EN
14387)
respirator
cartridges
as
a
backup
to
engineering
controls.
If
the
respirator
is
the
sole
means
of
protection,
use
a
full-face
supplied
air
respirator.
Use
respirators
and
components
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
CEN
(EU).
9.
9.1
PHYSICAL
AND
CHEMICAL
PROPERTIES
Information
on
basic
physical
and
chemical
properties
a)
b)
c)
d)
e)
f)
g)
h)
Appearance
Odour
Odour
Threshold
pH
Melting
point/freezing
point
Initial
boiling
point
and
boiling
range
Flash
point
Evaporation
rate
Form:
liquid
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
-17
??C
-
closed
cup
no
data
available
i)
Flammability
(solid,
gas)
no
data
available
j)
k)
l)
Upper/lower
flammability
or
explosive
limits
Vapour
pressure
Vapour
density
no
data
available
no
data
available
no
data
available
m)
Relative
density
no
data
available
n)
o)
p)
q)
r)
s)
t)
Water
solubility
Partition
coefficient:
n-
octanol/water
Autoignition
temperature
Decomposition
temperature
Viscosity
Explosive
properties
Oxidizing
properties
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
9.2
Other
safety
information
no
data
available
10.
10.1
10.2
10.3
10.4
10.5
10.6
11.
11.1
STABILITY
AND
REACTIVITY
Reactivity
no
data
available
Chemical
stability
no
data
available
Possibility
of
hazardous
reactions
no
data
available
Conditions
to
avoid
Heat,
flames
and
sparks.
Extremes
of
temperature
and
direct
sunlight.
Incompatible
materials
Bases,
Oxidizing
agents,
Reducing
agents,
Acetone
reacts
violently
with
phosphorous
oxychloride.
Hazardous
decomposition
products
Other
decomposition
products
-
no
data
available
TOXICOLOGICAL
INFORMATION
Information
on
toxicological
effects
Acute
toxicity
no
data
available
Skin
corrosion/irritation
no
data
available
Serious
eye
damage/eye
irritation
no
data
available
Respiratory
or
skin
sensitization
no
data
available
Germ
cell
mutagenicity
no
data
available
Carcinogenicity
IARC:
No
component
of
this
product
present
at
levels
greater
than
or
equal
to
0.1%
is
identified
as
probable,
possible
or
confirmed
human
carcinogen
by
IARC.
Reproductive
toxicity
no
data
available
Specific
target
organ
toxicity
-
single
exposure
no
data
available
Specific
target
organ
toxicity
-
repeated
exposure
no
data
available
Aspiration
hazard
no
data
available
Potential
health
effects
Inhalation
Ingestion
Skin
Eyes
May
be
harmful
if
inhaled.
May
cause
respiratory
tract
irritation.
Vapours
may
cause
drowsiness
and
dizziness.
May
be
harmful
if
swallowed.
May
be
harmful
if
absorbed
through
skin.
May
cause
skin
irritation.
Causes
serious
eye
irritation.
Signs
and
Symptoms
of
Exposure
To
the
best
of
our
knowledge,
the
chemical,
physical,
and
toxicological
properties
have
not
been
thoroughly
investigated.
Additional
Information
RTECS:
Not
available
12.
12.1
12.2
12.3
12.4
12.5
12.6
13.
13.1
14.
14.1
ECOLOGICAL
INFORMATION
Toxicity
no
data
available
Persistence
and
degradability
no
data
available
Bioaccumulative
potential
no
data
available
Mobility
in
soil
no
data
available
Results
of
PBT
and
vPvB
assessment
no
data
available
Other
adverse
effects
no
data
available
DISPOSAL
CONSIDERATIONS
Waste
treatment
methods
Product
Burn
in
a
chemical
incinerator
equipped
with
an
afterburner
and
scrubber
but
exert
extra
care
in
igniting
as
this
material
is
highly
flammable.
Offer
surplus
and
non-recyclable
solutions
to
a
licensed
disposal
company.
Contaminated
packaging
Dispose
of
as
unused
product.
TRANSPORT
INFORMATION
UN
number
14.2
14.3
14.4
14.5
14.6
15.
ADR/RID:
1090
UN
proper
shipping
name
ADR/RID:
ACETONE
IMDG:
ACETONE
IATA:
Acetone
Transport
hazard
class(es)
ADR/RID:
3
Packaging
group
ADR/RID:
II
Environmental
hazards
ADR/RID:
no
Special
precautions
for
user
no
data
available
REGULATORY
INFORMATION
IMDG:
1090
IMDG:
3
IMDG:
II
IMDG
Marine
pollutant:
no
IATA:
1090
IATA:
3
IATA:
II
IATA:
no
This
safety
datasheet
complies
with
the
requirements
of
Regulation
(EC)
No.
1907/2006.
15.1
15.2
16.
Safety,
health
and
environmental
regulations/legislation
specific
for
the
substance
or
mixture
no
data
available
Chemical
Safety
Assessment
no
data
available
OTHER
INFORMATION
Text
of
H-code(s)
and
R-phrase(s)
mentioned
in
Section
3
EUH066
Repeated
exposure
may
cause
skin
dryness
or
cracking.
Eye
Irrit.
Flam.
Liq.
H225
H319
H336
STOT
SE
F
Xi
R11
R36
R66
R67
Eye
irritation
Flammable
liquids
Highly
flammable
liquid
and
vapour.
Causes
serious
eye
irritation.
May
cause
drowsiness
or
dizziness.
Specific
target
organ
toxicity
-
single
exposure
Highly
flammable
Irritant
Highly
flammable.
Irritating
to
eyes.
Repeated
exposure
may
cause
skin
dryness
or
cracking.
Vapours
may
cause
drowsiness
and
dizziness.
Further
information
The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.
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PROSTAGLANDIN H2