Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one,
3,7-dihydro-6,7-dimethyl-5-phenyl-

CAS  

 57435-86-6

SYNONYMS  

 * 3,7-Dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)(1,4)diazepin-2(1H)-one
* MDL 181
* Premazepam

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UY8558000
CHEMICAL NAME           : Pyrrolo(3,4-e)(1,4)diazepin-2(1H)-one,
                          3,7-dihydro-6,7-dimethyl-5-phenyl-
CAS REGISTRY NUMBER     : 57435-86-6
BEILSTEIN REFERENCE NO. : 0617435
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H15-N3-O
MOLECULAR WEIGHT        : 253.33
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3,7-Dihydro-6,7-dimethyl-5-phenylpyrrolo(3,4-e)(1,4)diazepin-2(1H)-one
   * MDL 181
   * Premazepam
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 11,217,1976
 
                            *** END OF RECORD ***