6H-Cyclohepta(b)quinoline,
7,8,9,10-tetrahydro-11-amino-

CAS  

 5778-86-9

SYNONYMS  

 * MAS 111
* 7,8,9,10-Tetrahydro-11-amino-6H-cyclohepta(b)quinoline

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU3514100
CHEMICAL NAME           : 6H-Cyclohepta(b)quinoline,
                          7,8,9,10-tetrahydro-11-amino-
CAS REGISTRY NUMBER     : 5778-86-9
BEILSTEIN REFERENCE NO. : 0474991
REFERENCE               : 5-22-10-00499 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H16-N2
MOLECULAR WEIGHT        : 212.32
WISWESSER LINE NOTATION : T C667 BN&&TJ IZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * MAS 111
   * 7,8,9,10-Tetrahydro-11-amino-6H-cyclohepta(b)quinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 26,318,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 146,406,1963
 
                            *** END OF RECORD ***