Conforms to 93/112/EC and ISO 11014-1


SAFETY DATA SHEET
Order Number Customer Number


Identification of the substance/preparation and of the company/undertaking
1.
alpha-Conotoxin MI, Conus magus : 234623
Product name : Catalog #
: EMD Biosciences, Inc.
Supplier
10394 Pacific Center Court
Chemical formula C58H88N22O17S4
:
San Diego, CA 92121
(858)450-5558/(800)854-3417
FAX: (858)453-3552

alpha-CgTx MI
Synonym :




Emergency telephone : Call Chemtrec?
number (800)424-9300 (within U.S.A.)
(703)527-3887 (outside U.S.A.)


Composition / information on ingredients
2.
: Substance
Substance/Preparation

Chemical name* CAS No. EC Number Symbol R-Phrases
alpha-CgTx MI 83481-45-2 Not available. T+ R27/28



Hazards identification
3.
: Not applicable.
Physical/chemical hazards
: DANGER!
Human health hazards
MAY BE FATAL IF ABSORBED THROUGH SKIN OR IF SWALLOWED.
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: BLOOD.


First-aid measures
4.
First-Aid measures
: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
Inhalation
attention.
: If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
: In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Cold water may
Skin Contact
be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
Eye Contact
minutes. Cold water may be used. Get medical attention.

Effects and symptoms
: Extremely hazardous in case of ingestion. May be fatal if swallowed.
Ingestion
: Extremely hazardous in case of skin contact (permeator). Severe over-exposure can result in death.
Skin Contact
: Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
Aggravating conditions
many human organs.



5. Fire-fighting measures
: May be combustible at high temperature.
Flammability of the Product
Extinguishing Media
: SMALL FIRE: Use DRY chemical powder.
Suitable
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
Hazardous thermal (de)composition
products

: Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.
Special fire-fighting procedures
: Be sure to use an approved/certified respirator or equivalent.
Protection of fire-fighters




234623
Catalog #
 Accidental release measures
6.
: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid
Personal precautions
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Small Spill and Leak


: Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce
Large Spill and Leak
vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Call
for assistance on disposal.

Handling and storage
7.
: Keep locked up. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate
Handling
the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Avoid
contact with skin. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container
or the label.
: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20??C (-4??F).
Storage
Packaging materials
: Use original container.
Recommended use


Exposure controls/personal protection
8.
: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering measures
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne
contaminants below the exposure limit.
: Wash hands, forearms, and face thoroughly after handling compounds and before eating, smoking, using lavatory, and at
Hygiene measures
the end of day.
Ingredient Name Occupational Exposure Limits
alpha-Conotoxin MI, Conus magus Not available.


Personal protective equipment
: Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Respiratory system
: Lab coat.
Skin and body
: Gloves.
Hands
: Safety glasses.
Eyes
Protective Clothing (Pictograms) :




Physical and chemical properties
9.
: Solid. (Solid powder.)
Physical state
Color : White.
: 1493.7 g/mole
Molecular Weight

: Easily soluble in cold water.
Solubility
Flash point : Not available.
: Risks of explosion of the product in presence of mechanical impact: Not available.
Explosive properties
Risks of explosion of the product in presence of static discharge: Not available.



10. Stability and reactivity
: The product is stable.
Stability
: Not available.
Conditions to avoid
: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
Hazardous Decomposition Products




234623
Catalog #
 11. Toxicological information
RTECS # : N/A
Local effects
Skin irritation : Not available.
: LD50: Not available.
Acute toxicity
LC50: Not available.
: Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation in one or
Chronic toxicity
many human organs.
: Toxic for humans or animal life.
Other Toxic Effects on Humans
Extremely hazardous in case of skin contact (permeator), of ingestion.

May be fatal, if the substance enters bloodstream.

To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated.


Carcinogenic effects : Not available.
: Not available.
Mutagenic effects
Reproduction toxicity : Not available.
: Not available.
Teratogenic effects


12. Ecological information
: Not available.
Ecotoxicity
: The products of degradation are less toxic than the product itself.
Toxicity of the Products of
Biodegradation


13. Disposal considerations
: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Methods of disposal; Waste of residues;
Contaminated packaging



14. Transport information
International transport regulations
: UN2811
UN number
Land - Road/Railway
: Toxic solid, organic, n.o.s.*
Proper shipping name
: CLASS 6.1: Toxic substance.
ADR/RID Class

:I
Packing Group
ADR/RID label :




Sea
: Toxic solid, organic, n.o.s.*
Proper shipping name
: CLASS 6.1: Toxic substance.
IMDG Class

:I
Packing Group
IMDG label :




Air
: Toxic solid, organic, n.o.s.*
Proper shipping name
: UN2811
UN/ID Number
: CLASS 6.1: Toxic substance.
IATA-DGR Class

:I
Packing Group
IATA label :




: Not available.
Special Provisions for
Transport
234623
Catalog #
 15. Regulatory information
EU Regulations
Hazard symbol(s) :




: Very toxic
Classification
: R27/28- Very toxic in contact with skin and if swallowed.
Risk Phrases
: S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.
Safety Phrases
S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
: - alpha-Conotoxin MI, Conus magus
Contains
U.S. Federal Regulations : TSCA: No products were found.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
: CLASS: Highly toxic.
HCS Classification
CLASS: Target organ effects.

State Regulations :


: Not controlled under WHMIS (Canada).
WHMIS (Canada)
No products were found.


16. Other information
Hazardous Material * 0 National Fire
Health
Fire Hazard
1
Information System Protection Association
1
Fire Hazard
(U.S.A.) (U.S.A.) 0 0
Health Reactivity
0
Reactivity
Specific Hazard
E
Personal Protection
Personal Protection

Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries assumes any
liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with
caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. **This product is intended for research
use only.**

234623
Catalog # Date of issue 1/11/2005.


Conotoxin M I (reduced)