Avocado Research Chemicals Ltd - Material Safety Data Sheet 20198
1. IDENTIFICATION OF SUBSTANCE AND SUPPLIE Name On Label 1-(2-Chlorophenyl)biguanide hydrochloride
Product Number 20198
Supplier Johnson Matthey Catalog Company Inc.
30 Bond Street, Ward Hill, Massachusetts, 01835-8099
Emergency Telephone Number: (978) 521-6300; CHEMTREC: (800) 424-9300

Alternative Names None in common use.

2. COMPOSITION AND INFORMATION ON COMPONENTS
Name 1-(2-Chlorophenyl)biguanide hydrochloride
Minor Impurities Not determined
CAS No. 19579-44-3 EINECS No. Not listed EEC No.

3. HAZARDS IDENTIFICATION
Designation IRRITANT
Risk Phrases R36/37/38 Irritating to eyes, respiratory system and skin.

4. FIRST AID MEASURES
Inhalation Remove to fresh air. If breathing is difficult give oxygen and seek medical attention.
Eye Contact Flush with copious amounts of water for at least 15 minutes. If irritation persists, seek medical
attention.
Skin Contact Remove contaminated clothing. Wash affected area with soap and water. Rinse thoroughly. If
irritation persists or other symptoms are observed, seek medical advice.
Ingestion Rinse out mouth and drink lots of water. In case of irritation or other symptoms, seek medical
attention.

5. FIRE FIGHTING MEASURES
Extinguishing Medium Use fire fighting measures which suit the environment and take into account other materials which
may be involved. In general, water-based extinguishers should not be used for fires involving
organic materials. Use carbon dioxide or dry powder.
Protective Equipment Wear self-contained breathing apparatus and protective clothing.
Hazardous Products of Combustion may include: carbon monoxide, carbon dioxide, hydrogen chloride (hydrochloric acid),
oxides of nitrogen, nitric acid, hydrogen chloride (hydrochloric acid), hydrogen cyanide.

6. ACCIDENTAL RELEASE MEASURES
Personal Protection Wear protective equipment including rubber gloves, and eye protection. Keep unprotected persons
away.
Environmental Protection Take precautions to ensure product does not contaminate the ground or enter the drainage system.
Collection Mix with vermiculite or proprietary absorbent material and transfer to sealed containers for disposal.

7. HANDLING AND STORAGE
Handling Chemicals should be used only by those trained in handling potentially hazardous materials. Rubber
gloves, eye protection and protective clothing should be worn. Operations should be carried out in
an efficient fume hood or equivalent system.
Storage Store in tightly sealed containers in a cool place.
Product is hygroscopic. Take precautions to avoid contact with atmospheric moisture.

8. EXPOSURE CONTROLS AND PERSONAL PROTECTION
Respiratory Avoid inhalation of product. Handle in an efficient fume hood or equivalent system.
Eye Avoid eye contact. Wear safety spectacles, goggles or, for larger quantities, a full face mask.
Hands and Body Irritant product. Avoid skin contact. Wear rubber gloves, protective clothing and, for larger
quantities, full arm, body and face protection. Wash hands thoroughly after handling.




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20198 continued.
9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance Solid
Physical Constants m.p. 231-234?
Molecular formula C8H10ClN5.HCl Formula Wt. 248.12
Water solubility Density Not available
Flash Point Not available

10. STABILITY AND REACTIVITY
Specific Hazard

Incompatibilities Strong oxidising agents.
Decomposition Hazardous products of decomposition may include: carbon monoxide, carbon dioxide, hydrogen
chloride (hydrochloric acid), oxides of nitrogen, nitric acid, hydrogen chloride (hydrochloric acid),
hydrogen cyanide.

11. TOXICOLOGICAL INFORMATION
RTECS No. DU1780100
Acute Toxicity LD50: IPR-MUS 267mg/kg
Irritating to eyes, respiratory system and skin.

12. ECOLOGICAL EFFECTS
General Take care to prevent chemicals from entering the ground, water courses or drainage systems.

13. DISPOSAL CONSIDERATIONS
Disposal Disposal should be via an approved contractor and should take full account of local regulations.

14. TRANSPORT INFORMATION
UN Number
Land Transport ADR/RIC Code/Class Not Restricted
Maritime Transport IMDG Code/Class Not Restricted
Air Transport IATA Code/Class Not Restricted

15. REGULATORY INFORMATION
CAS No. 19579-44-3 EINECS No. Not listed EEC No. UN No. None RTECS No. DU1780100
Hazard Indication IRRITANT
Risk & Safety Phrases Irritating to eyes, respiratory system and skin.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
TSCA Not listed. For research and development use only.

16. OTHER INFORMATION
It must be recognised that the physical and chemical properties of any product may not be fully understood and that new,
possibly hazardous products may arise from reactions between chemicals. The information given in this data sheet is based
on our present knowledge and shall not constitute a guarantee for any specific product features and shall not establish a
legally valid contractual relationship.
Date of Last Review: 3rd August 1998 Date Printed: 18th September 1998


1-(2-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE