CAS : 197587-31-8
8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 1 ..................................................... PRODUCT IDENTIFICATION .........................................................................
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
SECTION 2 .................................. COMPOSITION, INFORMATION ON INGREDIENTS ......................................................
Synonyms
HS-??CD; beta-Cyclodextrin, 6A, 6B, 6C, 6D, 6E, 6F, 6G-heptakis (hydrogen sulfate), heptasodium salt
CAS #: 197587-31-8 MF: C42H70O56S7 x7Na
Ingredients Concentration (%/wt)
HS-??CD (197587-31-8)................................................................................................................. NLT 95 %
Manufacturing Impurities.............................................................................................................. NMT 5%
SECTION 3 ...................................................... HAZARDS IDENTIFICATION .........................................................................
Precautionary Statements See Sections 8 and 11 for further details.
The properties of this material have not been fully investigated. Use due caution in handling and use of
this material.
....................................................... Emergency Overview ........................................................
NFPA Ratings (Scale 0-4); Health = 1; Fire = 1; Reactivity = 0;
Solid: white to off white powder/crystals
Irritating to skin, eyes, mucous membranes, and upper respiratory tract. Harmful if ingested
or inhaled.
The properties of this material have not been fully investigated. Use due caution in
handling and use of this material.
May emit toxic fumes under fire conditions--potential chemical or thermal decomposition
products: carbon monoxide, carbon dioxide, sulfur oxides
Standard chemical handling precautions: Avoid ingestion or breathing dust. Avoid contact
with eyes, skin, and clothing. Wash thoroughly after handling.
Target organs: undetermined. This is an polysaccharide derivative.
See Sections 4, 5, 6, 8, 9, and 10.
....................................................................................................................................................
Other Hazard Information
This compound has not fully been tested for toxicological, irritation, or similar tendencies.
Primary Route(s) of Entry: Ingestion, Eye or Skin contact, Dust inhalation
Eye: May be irritating.
Skin: May be irritating.
Inhalation: May be irritating to respiratory system and mucous membranes. May be harmful.
Ingestion: May be harmful.
Acute: No data available.
Chronic: No data available.
Symptoms: See specific route above. Pre-existing conditions that may be aggravated: undetermined.
See Section 11 for additional toxicological data.
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 4 .......................................................... FIRST AID MEASURES .............................................................................
Eye contact: Immediately flush eyes with copious amounts of water or eyewash solution for at least 15
minutes; lift eyelids occasionally. If irritation persists, consult physician.
Skin contact: Immediately remove contaminated clothing and shoes, then wash skin with soap and copious
amounts of water. If irritation persists, consult physician.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration and keep person warm and at
rest. If breathing is difficult, give oxygen; consult physician.
Ingestion: Wash out mouth with water provided person is conscious; consult physician.
Wash contaminated clothing before reuse.
Physician note: Symptomatic and supportive care. No specific antidote known. Treatment based on physician
judgment in response to reactions of the patient.
SECTION 5 ..................................................... FIRE FIGHTING MEASURES.........................................................................
Flash Point: NA Method: NA Autoignition: NE
OSHA Flammability Class: NA Explosion Limits: upper: NE
NFPA: See Section 3 Hazards Identification Emergency Overview above. lower: NE
Extinguishing Media
Water, carbon dioxide, dry chemical powder, or appropriate foam.
Special or Standard Fire Fighting Procedures
Standard precautions for fighting large fires involving chemicals: Wear self-contained breathing apparatus (SCBA)
and protective clothing to prevent contact with skin and eyes.
Standard Fire and Explosion Hazards
Slight fire hazard--fire is possible with most organic compounds at elevated temperatures or from contact with an
ignition source.
Explosion potential unknown--If a substance is an organic solid, fine dust dispersed in air in sufficient
concentrations in the presence of an ignition source is a potential for a dust explosion.
Avoid inhalation of material or combustion by-products.
Unusual Fire and Explosion Hazards
None
Hazardous Combustion or Decomposition Products
May emit carbon monoxide, carbon dioxide, sulfur oxides
SECTION 6 .............................................. ACCIDENTAL RELEASE MEASURES..................................................................
Eliminate all ignition sources; slight fire hazard.
Evacuate unnecessary people from area. Isolate spilled material.
Ventilate area.
Wear protective clothing to prevent contact with skin and eyes (lab coat, gloves, and safety glasses).
Wear NIOSH/MSHA approved respirator for dust to prevent potential inhalation irritation.
If in solution, mix with sand or similar adsorbent material.
Sweep up, seal in appropriate hazardous waste container, and hold for proper waste disposal.
Avoid raising dust.
Wash spill site after material pickup is complete.
Standard chemical precautions: Keep out of water supplies and sewers.
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 7 ...................................................... HANDLING AND STORAGE..........................................................................
General Handling Measures
See Section 8 Below.
General Storage Measures
Store in a cool, dry place with adequate ventilation.
Minimize dust.
Avoid ignition and heat sources.
Special Storage Instructions
None
Special Handling Instructions
None
SECTION 8 ................................. EXPOSURE CONTROLS, PERSONAL PROTECTION.....................................................
Airborne Exposure Limits TWA (8H) STEL Ceiling Limit Ceiling (skin)
3 3 3 3
ppm mg/m ppm mg/m ppm mg/m ppm mg/m
OSHA NE NE NE NE NE NE NE NE
HS-??C PEL/VPEL
197587-31-8 ACGIH - TLV NE NE NE NE NE NE NE NE
Special/Other Control Measures
Odor threshold: NE
Personal Protective Equipment (PPE)
Chemical safety eyewear
Compatible chemical-resistant gloves
NIOSH/MSHA approved respirator with appropriate protections to prevent dust inhalation.
Protective Clothing (e.g., lab coat)
Other Standard Safety Equipment and Engineering Preventive Measures
Safety shower and eye wash
Mechanical exhaust
General Precautions and Handling Measures
Avoid ingestion, inhalation and contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure. Wash thoroughly after handling.
Wash contaminated clothing before reuse. Discard contaminated footware.
SECTION 9 .......................................... PHYSICAL AND CHEMICAL PROPERTIES .............................................................
Chemical Family: Polysaccharide Use: Analytical: buffered charged analyte for capillary electrophoresis
Appearance, Odor, and Other Properties
Appearance: white to off white powder/crystals
FW: 1856.36 MP: 183-187 C dec (361-368 F dec)
Odor: NE Water Reactive: No
bp (@ 1 atm): NA Solubility in Water: Miscible
VP (mmHg): NA Specific Gravity (H20 = 1.0): >1.0
% Volatiles: NE Evap. Rate (BuAc = 1.0): NA
Refractive Index: NE Vapor Density (Air = 1.0): NA
Solubility in Organic Solvents: NE
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 10 .................................................. STABILITY AND REACTIVITY ........................................................................
Stability
Stable.
Incompatibilities
Strong Oxidizers
Precautions
Avoid incompatibilities. Avoid generating dust.
Keep out of water supplies and sewers.
Hazardous Combustion or Decomposition Products
May emit carbon monoxide, carbon dioxide, sulfur oxides
Hazardous Polymerization
None
SECTION 11 ............................................... TOXICOLOGICAL INFORMATION.....................................................................
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
RTECS # CAS #
Only selected Registry of Toxic Effects of Chemical
None 197587-31-8
HS-??C Heptakis (2,6-di-O-methyl)- Substances data (RTECS) is presented here. See
GU2293500 51166-71-3
??-cyclodextrin*
actual entry in RTECS for complete information.
* Sister compound??reference only.
Irritation Data eye skin
NDA NDA
HS-??C Heptakis (2,6-di-O-methyl)- NDA NDA
??-cyclodextrin*
* Sister compound??reference only.
Toxicity Data oral inhalation dermal or other
NDA NDA NDA
HS-??C Heptakis (2,6-di-O-methyl)- orl mus LD > 3 g/kg NDA scs rat LD50 350 mg/kg;
inv rat LD50 220 mg/kg;
??-cyclodextrin*
inv mus LD >150 mg/kg
* Sister compound??reference only.
OSHA IARC NTP ACGIH NIOSH
Carcinogenicity Notes
NL NL NL NL NL None
HS-??C Heptakis (2,6-di-O-methyl)- NL NL NL NL NL None
??-cyclodextrin*
* Sister compound??reference only.
Teratogenicity
No data available
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
Reproductive Effects
No data available
Mutagenicity
No data available
Miscellaneous
No data available
Acute and Chronic Effects
See specific route responses in Section 3 Hazards Identification above.
SECTION 12 .................................................. ECOLOGICAL INFORMATION........................................................................
No known ecological hazards.
Standard Chemical Precautions
Keep out of water, air, and soil.
SECTION 13 ................................................. DISPOSAL CONSIDERATIONS.......................................................................
That which cannot be recovered or recycled, should be disposed of in accordance with all applicable Federal, State, and
local environmental regulations.
RCRA waste code(s): None RCRA Hazard Class (40CFR 261): None
SECTION 14 ................................................... TRANSPORT INFORMATION ........................................................................
Ship in accordance with all applicable local, State, Federal, and International transportation regulations.
The following is a summary only. Check regulations for complete information:
U. S. Department of Transportation (49CFR171.101)
Hazard Class or Division: Not regulated.
Land Transport ADR/RID: Not regulated.
Air Transport IATA/ICAO: Not regulated.
Maritime Transport IMDG: Not regulated.
SECTION 15 ................................................. REGULATORY INFORMATION .......................................................................
Reviews, Standards, and Regulations
................................................................. Heptakis-6-sulfato-beta-cyclodextrin sodium salt
CAS Number ........................................................................197587-31-8
TSCA: .................................................................................................N*
*This is sold strictly for research and development use .............. NA
EINECS:.............................................................................................. N
Number........................................................................................ NA
CERCLA [Section 103 (40 CFR 302.4)]:........................................... NL
RQ (lbs) ....................................................................................... NA
RCRA Waste Code ..................................................................... NA
OSHA Process Safety [29 CFR 1910.119]: ...................................... NL
State Lists: ......................................................................................... NL
States ....................................................................NL on CA, PA, MN, MA, FL, NJ
CA No Significant Risk Level....................................................... NL
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
................................................................. Heptakis-6-sulfato-beta-cyclodextrin sodium salt
CAS Number ........................................................................197587-31-8
Clean Air Act
[Section 112r (40 CFR 68)]:......................................................... NL
TQ (lbs) .................................................................................. NA
Contains Ozone Depleters (Class I or Class II)........................... NL
Clean Air Act [Section 103 (40 CFR 302.4)]:.............................. NL
SARA Title III Notification [40 CFR 302.4]:
Section 302/304 (EHS) Ingredient [40 CFR 355.3] ..................... NL
TPQ (lbs ................................................................................. NA
RQ (lbs) .................................................................................. NA
Section 313 Ingredient [40 CFR 372.65] ..................................... NL
Hazard Classes
Sara Acute Chronic Fire Pressure Reactivity
Title III N N N N N
Health Flammability Reactivity Special Hazards
NFPA 1 1 0 None
HMIS 1 1 0 None
Risk Phrases:
Caution: The properties of this material have not been fully investigated.
Safety Phrases:
S22/24/25--Do not breathe dust. Avoid contact with skin and eyes.
S26--In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
SECTION 16 ........................................................ OTHER INFORMATION..............................................................................
Miscellaneous
The health and toxicological hazards of this compound have not been fully investigated; therefore, this substance
must be handled only by, or under close supervision of those qualified in the handling and use of potentially
hazardous substances.
This MSDS was revised as follows:
A new catalog number was added to the original MSDS.
Disclaimer
The above information is believed to be correct, but does not purport to be all-inclusive and shall be used only as a
guide. Regis Technologies, Inc., does not guarantee said information is accurate or complete, nor shall any of this
information constitute a warranty, whether expressed or implied, as to the safety of the goods, the merchantability
of the goods, or the fitness of the goods for a particular purpose. Adjustment may be required to conform to the
actual conditions of usage. Regis Technologies, Inc. shall not be held liable for any damage resulting from
handling or from contact with the above product, nor for the results obtained, or for incidental or consequential
damage arising from the use of these data. No freedom from infringement of any patent, copyright or trademark is
to be inferred.
Approved of by: MBF This is the last page of this MSDS.
Reviewed and re-approved of with minor changes to the footer abbreviations and format.
by: M. Bryce-Fritts, CHMM 01/07/2005
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 1 ..................................................... PRODUCT IDENTIFICATION .........................................................................
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
SECTION 2 .................................. COMPOSITION, INFORMATION ON INGREDIENTS ......................................................
Synonyms
HS-??CD; beta-Cyclodextrin, 6A, 6B, 6C, 6D, 6E, 6F, 6G-heptakis (hydrogen sulfate), heptasodium salt
CAS #: 197587-31-8 MF: C42H70O56S7 x7Na
Ingredients Concentration (%/wt)
HS-??CD (197587-31-8)................................................................................................................. NLT 95 %
Manufacturing Impurities.............................................................................................................. NMT 5%
SECTION 3 ...................................................... HAZARDS IDENTIFICATION .........................................................................
Precautionary Statements See Sections 8 and 11 for further details.
The properties of this material have not been fully investigated. Use due caution in handling and use of
this material.
....................................................... Emergency Overview ........................................................
NFPA Ratings (Scale 0-4); Health = 1; Fire = 1; Reactivity = 0;
Solid: white to off white powder/crystals
Irritating to skin, eyes, mucous membranes, and upper respiratory tract. Harmful if ingested
or inhaled.
The properties of this material have not been fully investigated. Use due caution in
handling and use of this material.
May emit toxic fumes under fire conditions--potential chemical or thermal decomposition
products: carbon monoxide, carbon dioxide, sulfur oxides
Standard chemical handling precautions: Avoid ingestion or breathing dust. Avoid contact
with eyes, skin, and clothing. Wash thoroughly after handling.
Target organs: undetermined. This is an polysaccharide derivative.
See Sections 4, 5, 6, 8, 9, and 10.
....................................................................................................................................................
Other Hazard Information
This compound has not fully been tested for toxicological, irritation, or similar tendencies.
Primary Route(s) of Entry: Ingestion, Eye or Skin contact, Dust inhalation
Eye: May be irritating.
Skin: May be irritating.
Inhalation: May be irritating to respiratory system and mucous membranes. May be harmful.
Ingestion: May be harmful.
Acute: No data available.
Chronic: No data available.
Symptoms: See specific route above. Pre-existing conditions that may be aggravated: undetermined.
See Section 11 for additional toxicological data.
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 4 .......................................................... FIRST AID MEASURES .............................................................................
Eye contact: Immediately flush eyes with copious amounts of water or eyewash solution for at least 15
minutes; lift eyelids occasionally. If irritation persists, consult physician.
Skin contact: Immediately remove contaminated clothing and shoes, then wash skin with soap and copious
amounts of water. If irritation persists, consult physician.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration and keep person warm and at
rest. If breathing is difficult, give oxygen; consult physician.
Ingestion: Wash out mouth with water provided person is conscious; consult physician.
Wash contaminated clothing before reuse.
Physician note: Symptomatic and supportive care. No specific antidote known. Treatment based on physician
judgment in response to reactions of the patient.
SECTION 5 ..................................................... FIRE FIGHTING MEASURES.........................................................................
Flash Point: NA Method: NA Autoignition: NE
OSHA Flammability Class: NA Explosion Limits: upper: NE
NFPA: See Section 3 Hazards Identification Emergency Overview above. lower: NE
Extinguishing Media
Water, carbon dioxide, dry chemical powder, or appropriate foam.
Special or Standard Fire Fighting Procedures
Standard precautions for fighting large fires involving chemicals: Wear self-contained breathing apparatus (SCBA)
and protective clothing to prevent contact with skin and eyes.
Standard Fire and Explosion Hazards
Slight fire hazard--fire is possible with most organic compounds at elevated temperatures or from contact with an
ignition source.
Explosion potential unknown--If a substance is an organic solid, fine dust dispersed in air in sufficient
concentrations in the presence of an ignition source is a potential for a dust explosion.
Avoid inhalation of material or combustion by-products.
Unusual Fire and Explosion Hazards
None
Hazardous Combustion or Decomposition Products
May emit carbon monoxide, carbon dioxide, sulfur oxides
SECTION 6 .............................................. ACCIDENTAL RELEASE MEASURES..................................................................
Eliminate all ignition sources; slight fire hazard.
Evacuate unnecessary people from area. Isolate spilled material.
Ventilate area.
Wear protective clothing to prevent contact with skin and eyes (lab coat, gloves, and safety glasses).
Wear NIOSH/MSHA approved respirator for dust to prevent potential inhalation irritation.
If in solution, mix with sand or similar adsorbent material.
Sweep up, seal in appropriate hazardous waste container, and hold for proper waste disposal.
Avoid raising dust.
Wash spill site after material pickup is complete.
Standard chemical precautions: Keep out of water supplies and sewers.
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 7 ...................................................... HANDLING AND STORAGE..........................................................................
General Handling Measures
See Section 8 Below.
General Storage Measures
Store in a cool, dry place with adequate ventilation.
Minimize dust.
Avoid ignition and heat sources.
Special Storage Instructions
None
Special Handling Instructions
None
SECTION 8 ................................. EXPOSURE CONTROLS, PERSONAL PROTECTION.....................................................
Airborne Exposure Limits TWA (8H) STEL Ceiling Limit Ceiling (skin)
3 3 3 3
ppm mg/m ppm mg/m ppm mg/m ppm mg/m
OSHA NE NE NE NE NE NE NE NE
HS-??C PEL/VPEL
197587-31-8 ACGIH - TLV NE NE NE NE NE NE NE NE
Special/Other Control Measures
Odor threshold: NE
Personal Protective Equipment (PPE)
Chemical safety eyewear
Compatible chemical-resistant gloves
NIOSH/MSHA approved respirator with appropriate protections to prevent dust inhalation.
Protective Clothing (e.g., lab coat)
Other Standard Safety Equipment and Engineering Preventive Measures
Safety shower and eye wash
Mechanical exhaust
General Precautions and Handling Measures
Avoid ingestion, inhalation and contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure. Wash thoroughly after handling.
Wash contaminated clothing before reuse. Discard contaminated footware.
SECTION 9 .......................................... PHYSICAL AND CHEMICAL PROPERTIES .............................................................
Chemical Family: Polysaccharide Use: Analytical: buffered charged analyte for capillary electrophoresis
Appearance, Odor, and Other Properties
Appearance: white to off white powder/crystals
FW: 1856.36 MP: 183-187 C dec (361-368 F dec)
Odor: NE Water Reactive: No
bp (@ 1 atm): NA Solubility in Water: Miscible
VP (mmHg): NA Specific Gravity (H20 = 1.0): >1.0
% Volatiles: NE Evap. Rate (BuAc = 1.0): NA
Refractive Index: NE Vapor Density (Air = 1.0): NA
Solubility in Organic Solvents: NE
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
SECTION 10 .................................................. STABILITY AND REACTIVITY ........................................................................
Stability
Stable.
Incompatibilities
Strong Oxidizers
Precautions
Avoid incompatibilities. Avoid generating dust.
Keep out of water supplies and sewers.
Hazardous Combustion or Decomposition Products
May emit carbon monoxide, carbon dioxide, sulfur oxides
Hazardous Polymerization
None
SECTION 11 ............................................... TOXICOLOGICAL INFORMATION.....................................................................
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
RTECS # CAS #
Only selected Registry of Toxic Effects of Chemical
None 197587-31-8
HS-??C Heptakis (2,6-di-O-methyl)- Substances data (RTECS) is presented here. See
GU2293500 51166-71-3
??-cyclodextrin*
actual entry in RTECS for complete information.
* Sister compound??reference only.
Irritation Data eye skin
NDA NDA
HS-??C Heptakis (2,6-di-O-methyl)- NDA NDA
??-cyclodextrin*
* Sister compound??reference only.
Toxicity Data oral inhalation dermal or other
NDA NDA NDA
HS-??C Heptakis (2,6-di-O-methyl)- orl mus LD > 3 g/kg NDA scs rat LD50 350 mg/kg;
inv rat LD50 220 mg/kg;
??-cyclodextrin*
inv mus LD >150 mg/kg
* Sister compound??reference only.
OSHA IARC NTP ACGIH NIOSH
Carcinogenicity Notes
NL NL NL NL NL None
HS-??C Heptakis (2,6-di-O-methyl)- NL NL NL NL NL None
??-cyclodextrin*
* Sister compound??reference only.
Teratogenicity
No data available
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
Reproductive Effects
No data available
Mutagenicity
No data available
Miscellaneous
No data available
Acute and Chronic Effects
See specific route responses in Section 3 Hazards Identification above.
SECTION 12 .................................................. ECOLOGICAL INFORMATION........................................................................
No known ecological hazards.
Standard Chemical Precautions
Keep out of water, air, and soil.
SECTION 13 ................................................. DISPOSAL CONSIDERATIONS.......................................................................
That which cannot be recovered or recycled, should be disposed of in accordance with all applicable Federal, State, and
local environmental regulations.
RCRA waste code(s): None RCRA Hazard Class (40CFR 261): None
SECTION 14 ................................................... TRANSPORT INFORMATION ........................................................................
Ship in accordance with all applicable local, State, Federal, and International transportation regulations.
The following is a summary only. Check regulations for complete information:
U. S. Department of Transportation (49CFR171.101)
Hazard Class or Division: Not regulated.
Land Transport ADR/RID: Not regulated.
Air Transport IATA/ICAO: Not regulated.
Maritime Transport IMDG: Not regulated.
SECTION 15 ................................................. REGULATORY INFORMATION .......................................................................
Reviews, Standards, and Regulations
................................................................. Heptakis-6-sulfato-beta-cyclodextrin sodium salt
CAS Number ........................................................................197587-31-8
TSCA: .................................................................................................N*
*This is sold strictly for research and development use .............. NA
EINECS:.............................................................................................. N
Number........................................................................................ NA
CERCLA [Section 103 (40 CFR 302.4)]:........................................... NL
RQ (lbs) ....................................................................................... NA
RCRA Waste Code ..................................................................... NA
OSHA Process Safety [29 CFR 1910.119]: ...................................... NL
State Lists: ......................................................................................... NL
States ....................................................................NL on CA, PA, MN, MA, FL, NJ
CA No Significant Risk Level....................................................... NL
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1 8210 N. Austin Avenue, Morton Grove, IL 60053-0519, U.S.A.
847-967-6000 800-323-8144 Emergency Contact:
(Monday - Friday: 7:30 a.m. - 4:00 p.m. CST) INFOTRAC 800-535-5053 [U.S.A.]
Name: Heptakis-6-sulfato-??-cyclodextrin sodium salt
Code: 733400, 733410
....................................................................MATERIAL SAFETY DATA SHEET ....................................................................
................................................................. Heptakis-6-sulfato-beta-cyclodextrin sodium salt
CAS Number ........................................................................197587-31-8
Clean Air Act
[Section 112r (40 CFR 68)]:......................................................... NL
TQ (lbs) .................................................................................. NA
Contains Ozone Depleters (Class I or Class II)........................... NL
Clean Air Act [Section 103 (40 CFR 302.4)]:.............................. NL
SARA Title III Notification [40 CFR 302.4]:
Section 302/304 (EHS) Ingredient [40 CFR 355.3] ..................... NL
TPQ (lbs ................................................................................. NA
RQ (lbs) .................................................................................. NA
Section 313 Ingredient [40 CFR 372.65] ..................................... NL
Hazard Classes
Sara Acute Chronic Fire Pressure Reactivity
Title III N N N N N
Health Flammability Reactivity Special Hazards
NFPA 1 1 0 None
HMIS 1 1 0 None
Risk Phrases:
Caution: The properties of this material have not been fully investigated.
Safety Phrases:
S22/24/25--Do not breathe dust. Avoid contact with skin and eyes.
S26--In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
SECTION 16 ........................................................ OTHER INFORMATION..............................................................................
Miscellaneous
The health and toxicological hazards of this compound have not been fully investigated; therefore, this substance
must be handled only by, or under close supervision of those qualified in the handling and use of potentially
hazardous substances.
This MSDS was revised as follows:
A new catalog number was added to the original MSDS.
Disclaimer
The above information is believed to be correct, but does not purport to be all-inclusive and shall be used only as a
guide. Regis Technologies, Inc., does not guarantee said information is accurate or complete, nor shall any of this
information constitute a warranty, whether expressed or implied, as to the safety of the goods, the merchantability
of the goods, or the fitness of the goods for a particular purpose. Adjustment may be required to conform to the
actual conditions of usage. Regis Technologies, Inc. shall not be held liable for any damage resulting from
handling or from contact with the above product, nor for the results obtained, or for incidental or consequential
damage arising from the use of these data. No freedom from infringement of any patent, copyright or trademark is
to be inferred.
Approved of by: MBF This is the last page of this MSDS.
Reviewed and re-approved of with minor changes to the footer abbreviations and format.
by: M. Bryce-Fritts, CHMM 01/07/2005
Abbreviations: NA??not applicable; NE??not established; U??unknown/not available; NL??not listed; N??no; Y??yes.; NDA-No data available.
MSDS# 733400b1 Effective Date: 01/07/2005 Version #: 2.1
HEPTAKIS(6-O-SULFO)-(BETA)-CYCLODEXTRIN
China (Mainland)] 
Assessed
Assessed