Piperazineethanol, 4-(1-adamantyl)-, dihydrochloride

CAS  

 19984-41-9

SYNONYMS  

 * Adamantane, 1-(1-(4-hydroxyethyl)piperazinyl)-, dihydrochloride
* 1-(1-Adamantyl)-4-hydroxyethylpiperazine dihydrochloride
* Piperazine, 1-(1-adamantyl)-4-hydroxyethyl-, dihydrochloride

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL6830000
CHEMICAL NAME           : Piperazineethanol, 4-(1-adamantyl)-, dihydrochloride
CAS REGISTRY NUMBER     : 19984-41-9
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H28-N2-O.2Cl-H
MOLECULAR WEIGHT        : 337.38
WISWESSER LINE NOTATION : L66 B6/B-H/DI A B- C 1B ITJ B- AT6N DNTJ D2Q &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adamantane, 1-(1-(4-hydroxyethyl)piperazinyl)-, dihydrochloride
   * 1-(1-Adamantyl)-4-hydroxyethylpiperazine dihydrochloride
   * Piperazine, 1-(1-adamantyl)-4-hydroxyethyl-, dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - ataxia
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - reactivates cholinesterase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 11,355,1977
 
                            *** END OF RECORD ***