*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OM2000000
CHEMICAL NAME : Magnesate(1-), (L-aspartato(2-)-N,O(sup 1),O(sup
4))chloro-, hydrogen, (T-4), trihydrate
CAS REGISTRY NUMBER : 28184-71-6
OTHER CAS REGISTRY NOS. : 40158-10-9
LAST UPDATED : 199012
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C4-H5-Mg-N-O4.Cl-H.3H2-O
MOLECULAR WEIGHT : 245.93
SYNONYMS/TRADE NAMES :
* (L-Aspartato(2-)-N,O(sup 1),O(sup 4))chloromagnesate(1-) hydrogen (T-4)
trihydrate
* Magnesium aspartate hydrochloride trihydrate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4850 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia
Behavioral - muscle contraction or spasticity
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 216 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5566 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Behavioral - ataxia
Gastrointestinal - nausea or vomiting
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1020 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
Gastrointestinal - ulceration or bleeding from duodenum
REFERENCE :
NCDREP New Cardiovascular Drugs. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) 1985- Volume(issue)/page/year: 4,243,1986
*** END OF RECORD ***
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