Material Safety Data Sheet
Section 1. Product and Company Identification
Product Name (2R)-3,4-Dihydro-2H-1-benzopyrane-2- 8.14809
Product Code
methylaminehydrochloride for Synthesis
EMD Chemicals Inc.
Manufacturer Effective Date 10/5/2004
P.O. Box 70
12/22/2004
Print Date
480 Democrat Road
Gibbstown, NJ 08027
Prior to January 1, 2003 EMD Chemicals Inc. was EM
Industries, Inc. or EM Science, Division of EM Industries,
Inc.
For More Information Call In Case of Emergency Call
(914) 592-4660 800-424-9300 CHEMTREC (USA)
M-F, 9AM-4:30 PM EST 613-996-6666 (Canada)
24 Hours/Day: 7 Days/Week
(R)-2-Aminomethylchromane hydrochloride
Synonym
Laboratory Reagent
Material Uses


Organic
Chemical Family
Section 2. Composition and Information on Ingredients
Component CAS # % by
Weight
437763-66-1
(2R)-3,4-Dihydro-2H-1benzopyrane- 100
2-methylaminehydrochloride



Section 3. Hazards Identification
Solid.
Physical State and
Appearance
CAUTION !
Emergency Overview
HARMFUL IF SWALLOWED.
MAY BE HARMFUL IF INHALED.
MAY CAUSE EYE AND SKIN IRRITATION.
SUBSTANCE NOT YET FULLY TESTED.


Dermal contact. Eye contact. Inhalation. Ingestion.
Routes of Entry

Potential Acute Health Effects
Eyes May be hazardous in case of eye contact (irritant).
Skin May be hazardous in case of skin contact (irritant). Skin inflammation is characterized by
itching, scaling, reddening, or, occasionally, blistering.
Inhalation May be hazardous in case of inhalation.
Ingestion Hazardous in case of ingestion. Do not ingest.
Potential Chronic Health Effects
Carcinogenic Effects This material is not known to cause cancer in animals or humans.
Additional information See Toxicological Information (section 11)


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methylaminehydrochloride for
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Repeated exposure to a highly toxic material may produce general deterioration of health by an
Medical Conditions
accumulation in one or many human organs.
Aggravated by
Overexposure:

Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with
Eye Contact
plenty of water for at least 15 minutes. Get medical attention.
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an
Skin Contact
emollient. Remove contaminated clothing and shoes. Wash clothing before reuse.
Thoroughly clean shoes before reuse. Get medical attention.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical attention.
Ingestion If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give
anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or
waistband. Get medical attention immediately.

Section 5. Fire Fighting Measures
May be combustible at high temperature.
Flammability of the
Product
Not available.
Auto-ignition
Temperature
Not available.
Flash Points

Not available.
Flammable Limits

These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated
Products of Combustion
compounds.
Not available.
Fire Hazards in Presence
of Various Substances
Risks of explosion of the product in presence of static discharge: No.
Explosion Hazards in
Presence of Various
Risks of explosion of the product in presence of mechanical impact: No.
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Protective Clothing (Fire) Be sure to use an approved/certified respirator or equivalent.


Not available.
Special Remarks on Fire
Hazards
Development of hazardous combustion gases or vapors possible in the event of fire.
Special Remarks on
Explosion Hazards

Section 6. Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Small Spill and Leak

Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use
Large Spill and Leak
water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if
needed. Eliminate all ignition sources. Call for assistance on disposal. Finish cleaning by
spreading water on the contaminated surface and allow to evacuate through the sanitary
system.
No specific spill kit required for this product.
Spill Kit Information



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methylaminehydrochloride for
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Section 7. Handling and Storage
Avoid contact with eyes, skin and clothing. Do not ingest. Avoid breathing dust. Keep
Handling
container closed. Use only with adequate ventilation. Wash thoroughly after handling.
Keep container tightly closed. Keep in a well-ventilated place.
Storage

Section 8. Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep
Engineering Controls
airborne levels below recommended exposure limits. If user operations generate dust, fume or
mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection
Eyes Splash goggles.
Body Lab coat.
Respiratory Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Hands Gloves.
Feet Not applicable.
Protective Clothing
(Pictograms)




Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing
Personal Protection in
apparatus should be used to avoid inhalation of the product. Suggested protective clothing
Case of a Large Spill
might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits
Product Name
(2R)-3,4-Dihydro-2H-1benzopyrane- Not available.
2-methylaminehydrochloride

Section 9. Physical and Chemical Properties
Not available.
Odor

White.
Color

Solid.
Physical State and
Appearance
199.68 g/mole
Molecular Weight

C10H14CINO
Molecular Formula

Not available.
pH

Not available.
Boiling/Condensation
Point
Not available.
Melting/Freezing Point

Not available.
Specific Gravity

Vapor Pressure Not available.

Not available.
Vapor Density

Not available.
Odor Threshold


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methylaminehydrochloride for
Synthesis
Not available.
Evaporation Rate

Not available.
LogKow

Not available.
Solubility

Section 10. Stability and Reactivity
The product is stable.
Stability and Reactivity
Not available.
Conditions of Instability

Not available.
Incompatibility with
Various Substances
Avoid generating dust.
Rem/Incompatibility

Hazardous Decomposition These products are halogenated compounds.
Products
Hazardous Polymerization Not available.

Section 11. Toxicological Information
(2R)-3,4-Dihydro-2H-1benzopyrane
RTECS Number: Not available.
-2-methylaminehydrochloride
LD50: Not available.
Toxicity
LC50: Not available.
Not available.
Chronic Effects on
Humans
May be hazardous in case of eye contact (irritant). May be hazardous in case of skin contact
Acute Effects on Humans
(irritant). Skin inflammation is characterized by itching, scaling, reddening, or, occasionally,
blistering. May be hazardous in case of inhalation. Hazardous in case of ingestion.

Special Remarks on Other SUBSTANCE NOT YET FULLY TESTED.
Toxic Effects on Humans
Synergetic Products Not available.
(Toxicologically)
Irritancy Draize Test: Not available.

Sensitization Not available.

Carcinogenic Effects This material is not known to cause cancer in animals or humans.

Toxicity to Reproductive Not available.
System
Teratogenic Effects Not available.
Mutagenic Effects Not available.

Section 12. Ecological Information
Not available.
Ecotoxicity

Not available.
BOD5 and CO
Toxicity of the Products of The products of degradation are as toxic as the product itself.
Biodegradation



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methylaminehydrochloride for
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Section 13. Disposal Considerations
Not available.
EPA Waste Number

Material does not have an EPA Waste number and is not a listed waste, however consultation
Treatment
with a permitted waste disposal site (TSD) should be accomplished.
ALWAYS CONTACT A PERMITTED WASTE DISPOSER (TSD) TO ASSURE COMPLIANCE
WITH ALL CURRENT LOCAL, STATE AND FEDERAL REGULATIONS.
Section 14. Transport Information
Not available.
DOT Classification


Not available.
TDG Classification
Not available.
IMO/IMDG
Classification
Not available.
ICAO/IATA
Classification

Section 15. Regulatory Information
TSCA: Not Listed On the TSCA Inventory. For Research & Development Use Only. Not for
U.S. Federal Regulations
Manufacturing or Commercial Purposes.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were
found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
Not controlled under WHMIS (Canada).
WHMIS (Canada)

No products were found.
This product has been classifed in accordance with the hazard criteria of the Controlled Product
Regulations and the MSDS contains all required information.
International Regulations
Not available.
EINECS

R36/38- Irritating to eyes and skin.
DSCL (EEC)

International Lists No products were found.
China: No products were found.
State Regulations New Jersey: (2R)-3,4-Dihydro-2H-1benzopyrane-2-methylaminehydrochloride for Synthesis
California prop. 65: No products were found.




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Section 16. Other Information
National Fire Fire Hazard
0
Protection 1 0
Health Reactivity
Association
(U.S.A.) Specific Hazard




Changed Since Last +
Revision

Notice to Reader
The statements contained herein are based upon technical data that EMD Chemicals Inc. believes to be reliable, are offered for
information purposes only and as a guide to the appropriate precautionary and emergency handling of the material by a properly
trained person having the necessary technical skills. Users should consider these data only as a supplement to other information
gathered by them and must make independent determinations of suitability and completeness of information from all sources to
assure proper use, storage and disposal of these materials and the safety and health of employees and customers and the
protection of the environment. EMD CHEMICALS INC. MAKES NO REPRESENTATION OR WARRANTY OF ANY KIND,
EXPRESS OR IMPLIED, INCLUDING MERCHANTABILITY OR FITNESS FOR A PARTICULAR USE, WITH RESPECT TO
THE INFORMATION HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.


(2R)-3,4-DIHYDRO-2H-1-BENZOPYRANE-2-METHYL-AMINE HYDROCHLORIDE