Conhydrine

CAS  

 495-20-5

SYNONYMS  

 * (+)-Conhydrine
* (R-(R*,S*))-alpha-Ethyl-2-piperidinemethanol
* Oxyconine
* 2-Piperidinemethanol, alpha-ethyl-, (R-(R*,S*))-

                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GK8000000
CHEMICAL NAME           : Conhydrine
CAS REGISTRY NUMBER     : 495-20-5
BEILSTEIN REFERENCE NO. : 0080052
REFERENCE               : 5-21-01-00138 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C8-H17-N-O
MOLECULAR WEIGHT        : 143.26
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+)-Conhydrine
   * (R-(R*,S*))-alpha-Ethyl-2-piperidinemethanol
   * Oxyconine
   * 2-Piperidinemethanol, alpha-ethyl-, (R-(R*,S*))-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 400 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,593,1948
 
                            *** END OF RECORD ***