1.
1.1
IDENTIFICATION
OF
THE
SUBSTANCE/MIXTURE
AND
OF
THE
COMPANY/UNDERTAKING
Product
identifiers
Product
name
Product
Number
Brand
CAS-No.
:
:
:
:
Benzene-d6
236977
Anonymous
1076-43-3
1.2
Relevant
identified
uses
of
the
substance
or
mixture
and
uses
advised
against
Identified
uses
:
Laboratory
chemicals,
Manufacture
of
substances 2.
2.1
2.2
HAZARDS
IDENTIFICATION
Classification
of
the
substance
or
mixture
Classification
according
to
Regulation
(EC)
No
1272/2008
[EU-GHS/CLP]
Flammable
liquids
(Category
2)
Carcinogenicity
(Category
1A)
Germ
cell
mutagenicity
(Category
1B)
Specific
target
organ
toxicity
-
repeated
exposure
(Category
1)
Aspiration
hazard
(Category
1)
Eye
irritation
(Category
2)
Skin
irritation
(Category
2)
Classification
according
to
EU
Directives
67/548/EEC
or
1999/45/EC
Highly
flammable.
May
cause
cancer.
May
cause
heritable
genetic
damage.
Toxic:
danger
of
serious
damage
to
health
by
prolonged
exposure
through
inhalation,
in
contact
with
skin
and
if
swallowed.
Harmful:
may
cause
lung
damage
if
swallowed.
Irritating
to
eyes
and
skin.
Label
elements
Labelling
according
Regulation
(EC)
No
1272/2008
[CLP]
Pictogram
Signal
word
Hazard
statement(s)
H225
H304
H315
H319
Danger
Highly
flammable
liquid
and
vapour.
May
be
fatal
if
swallowed
and
enters
airways.
Causes
skin
irritation.
Causes
serious
eye
irritation.
H340
H350
H372
Precautionary
statement(s)
P201
P210
P301
+
P310
P305
+
P351
+
P338
P308
+
P313
P331
Supplemental
Hazard
May
cause
genetic
defects.
May
cause
cancer.
Causes
damage
to
organs
through
prolonged
or
repeated
exposure.
Obtain
special
instructions
before
use.
Keep
away
from
heat/sparks/open
flames/hot
surfaces.
-
No
smoking.
IF
SWALLOWED:
Immediately
call
a
POISON
CENTER
or
doctor/
physician.
IF
IN
EYES:
Rinse
cautiously
with
water
for
several
minutes.
Remove
contact
lenses,
if
present
and
easy
to
do.
Continue
rinsing.
IF
exposed
or
concerned:
Get
medical
advice/
attention.
Do
NOT
induce
vomiting.
none
Statements
Restricted
to
professional
users.
According
to
European
Directive
67/548/EEC
as
amended.
Hazard
symbol(s)
R-phrase(s)
R45
R46
R48/23/24/25
R65
R11
R36/38
S-phrase(s)
S53
S45
May
cause
cancer.
May
cause
heritable
genetic
damage.
Also
toxic:
danger
of
serious
damage
to
health
by
prolonged
exposure
through
inhalation,
in
contact
with
skin
and
if
swallowed.
Also
harmful:
may
cause
lung
damage
if
swallowed.
Highly
flammable.
Irritating
to
eyes
and
skin.
Avoid
exposure
-
obtain
special
instructions
before
use.
In
case
of
accident
or
if
you
feel
unwell,
seek
medical
advice
immediately
(show
the
label
where
possible).
Restricted
to
professional
users.
2.3
3.
3.1
Other
hazards
-
none
COMPOSITION/INFORMATION
ON
INGREDIENTS
Substances
Synonyms
Formula
Molecular
Weight
Component
Benzene-D6
:
:
:
Hexadeuterobenzene
C6D6
84,15
g/mol
Concentration
CAS-No.
EC-No.
1076-43-3
214-061-8
-
4.
4.1
FIRST
AID
MEASURES
Description
of
first
aid
measures
General
advice
Consult
a
physician.
Show
this
safety
data
sheet
to
the
doctor
in
attendance.
If
inhaled
If
breathed
in,
move
person
into
fresh
air.
If
not
breathing,
give
artificial
respiration.
Consult
a
physician.
In
case
of
skin
contact
Wash
off
with
soap
and
plenty
of
water.
Consult
a
physician.
In
case
of
eye
contact
Rinse
thoroughly
with
plenty
of
water
for
at
least
15
minutes
and
consult
a
physician.
If
swallowed
Do
NOT
induce
vomiting.
Never
give
anything
by
mouth
to
an
unconscious
person.
Rinse
mouth
with
water.
Consult
a
physician.
4.2
4.3
5.
5.1
5.2
5.3
5.4
6.
6.1
6.2
6.3
6.4
7.
7.1
Most
important
symptoms
and
effects,
both
acute
and
delayed
Nausea,
Dizziness,
Headache,
narcosis,
Inhalation
of
high
concentrations
of
benzene
may
have
an
initial
stimulatory
effect
on
the
central
nervous
system
characterized
by
exhilaration,
nervous
excitation
and/or
giddiness,
depression,
drowsiness,
or
fatigue.
The
victim
may
experience
tightness
in
the
chest,
breathlessness,
and
loss
of
consciousness.
Tremors,
convulsions,
and
death
due
to
respiratory
paralysis
or
circulatory
collapse
can
occur
in
a
few
minutes
to
several
hours
following
severe
exposures.
Aspiration
of
small
amounts
of
liquid
immediately
causes
pulmonary
edema
and
hemorrhage
of
pulmonary
tissue.
Direct
skin
contact
may
cause
erythema.
Repeated
or
prolonged
skin
contact
may
result
in
drying,
scaling
dermatitis,
or
development
of
secondary
skin
infections.
The
chief
target
organ
is
the
hematopoietic
system.
Bleeding
from
the
nose,
gums,
or
mucous
membranes
and
the
development
of
purpuric
spots,
pancytopenia,
leukopenia,
thrombocytopenia,
aplastic
anemia,
and
leukemia
may
occur
as
the
condition
progresses.
The
bone
marrow
may
appear
normal,
aplastic
or
hyperplastic,
and
may
not
correlate
with
peripheral
blood-forming
tissues.
The
onset
of
effects
of
prolonged
benzene
exposure
may
be
delayed
for
many
months
or
years
after
the
actual
exposure
has
ceased.,
Blood
disorders
Indication
of
any
immediate
medical
attention
and
special
treatment
needed
no
data
available
FIREFIGHTING
MEASURES
Extinguishing
media
Suitable
extinguishing
media
Use
water
spray,
alcohol-resistant
foam,
dry
chemical
or
carbon
dioxide.
Special
hazards
arising
from
the
substance
or
mixture
Carbon
oxides
Advice
for
firefighters
Wear
self
contained
breathing
apparatus
for
fire
fighting
if
necessary.
Further
information
Use
water
spray
to
cool
unopened
containers.
ACCIDENTAL
RELEASE
MEASURES
Personal
precautions,
protective
equipment
and
emergency
procedures
Use
personal
protective
equipment.
Avoid
breathing
vapors,
mist
or
gas.
Ensure
adequate
ventilation.
Remove
all
sources
of
ignition.
Evacuate
personnel
to
safe
areas.
Beware
of
vapours
accumulating
to
form
explosive
concentrations.
Vapours
can
accumulate
in
low
areas.
Environmental
precautions
Prevent
further
leakage
or
spillage
if
safe
to
do
so.
Do
not
let
product
enter
drains.
Methods
and
materials
for
containment
and
cleaning
up
Contain
spillage,
and
then
collect
with
an
electrically
protected
vacuum
cleaner
or
by
wet-brushing
and
place
in
container
for
disposal
according
to
local
regulations
(see
section
13).
Reference
to
other
sections
For
disposal
see
section
13.
HANDLING
AND
STORAGE
Precautions
for
safe
handling
Avoid
exposure
-
obtain
special
instructions
before
use.Avoid
contact
with
skin
and
eyes.
Avoid
inhalation
of
vapour
or
mist.
Keep
away
from
sources
of
ignition
-
No
smoking.Take
measures
to
prevent
the
build
up
of
electrostatic
charge.
7.2
7.3
8.
8.1
8.2
Conditions
for
safe
storage,
including
any
incompatibilities
Store
in
cool
place.
Keep
container
tightly
closed
in
a
dry
and
well-ventilated
place.
Containers
which
are
opened
must
be
carefully
resealed
and
kept
upright
to
prevent
leakage.
Handle
and
store
under
inert
gas.
hygroscopic
Specific
end
uses
no
data
available
EXPOSURE
CONTROLS/PERSONAL
PROTECTION
Control
parameters
Components
with
workplace
control
parameters
Exposure
controls
Appropriate
engineering
controls
Handle
in
accordance
with
good
industrial
hygiene
and
safety
practice.
Wash
hands
before
breaks
and
at
the
end
of
workday.
Personal
protective
equipment
Eye/face
protection
Face
shield
and
safety
glasses
Use
equipment
for
eye
protection
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
EN
166(EU).
Skin
protection
Handle
with
gloves.
Gloves
must
be
inspected
prior
to
use.
Use
proper
glove
removal
technique
(without
touching
glove's
outer
surface)
to
avoid
skin
contact
with
this
product.
Dispose
of
contaminated
gloves
after
use
in
accordance
with
applicable
laws
and
good
laboratory
practices.
Wash
and
dry
hands.
The
selected
protective
gloves
have
to
satisfy
the
specifications
of
EU
Directive
89/686/EEC
and
the
standard
EN
374
derived
from
it.
Immersion
protection
Material:
Fluorinated
rubber
Minimum
layer
thickness:
0,7
mm
Break
through
time:
>
480
min
Material
tested:Vitoject?
(Anonymous
Z677698,
Size
M)
Splash
protection
Material:
Fluorinated
rubber
Minimum
layer
thickness:
0,7
mm
Break
through
time:
>
30
min
Material
tested:Vitoject?
(Anonymous
Z677698,
Size
M)
data
source:
KCL
GmbH,
D-36124
Eichenzell,
phone
+49
(0)6659
873000,
e-mail
sales@kcl.de,
test
method:
EN374
If
used
in
solution,
or
mixed
with
other
substances,
and
under
conditions
which
differ
from
EN
374,
contact
the
supplier
of
the
CE
approved
gloves.
This
recommendation
is
advisory
only
and
must
be
evaluated
by
an
Industrial
Hygienist
familiar
with
the
specific
situation
of
anticipated
use
by
our
customers.
It
should
not
be
construed
as
offering
an
approval
for
any
specific
use
scenario.
Body
Protection
Complete
suit
protecting
against
chemicals,
Flame
retardant
antistatic
protective
clothing,
The
type
of
protective
equipment
must
be
selected
according
to
the
concentration
and
amount
of
the
dangerous
substance
at
the
specific
workplace.
Respiratory
protection
Where
risk
assessment
shows
air-purifying
respirators
are
appropriate
use
a
full-face
respirator
with
multi-purpose
combination
(US)
or
type
ABEK
(EN
14387)
respirator
cartridges
as
a
backup
to
engineering
controls.
If
the
respirator
is
the
sole
means
of
protection,
use
a
full-face
supplied
air
respirator.
Use
respirators
and
components
tested
and
approved
under
appropriate
government
standards
such
as
NIOSH
(US)
or
CEN
(EU).
9.
9.1
PHYSICAL
AND
CHEMICAL
PROPERTIES
Information
on
basic
physical
and
chemical
properties
a)
b)
c)
d)
e)
f)
g)
h)
Appearance
Odour
Odour
Threshold
pH
Melting
point/freezing
point
Initial
boiling
point
and
boiling
range
Flash
point
Evaporation
rate
Form:
liquid
Colour:
colourless
no
data
available
no
data
available
no
data
available
Melting
point/range:
6,8
°C
79,1
°C
at
1.013
hPa
-11
°C
-
closed
cup
no
data
available
i)
Flammability
(solid,
gas)
no
data
available
j)
k)
l)
Upper/lower
flammability
or
explosive
limits
Vapour
pressure
Vapour
density
Upper
explosion
limit:
8
%(V)
Lower
explosion
limit:
1,3
%(V)
221
hPa
at
37,7
°C
99,5
hPa
at
20
°C
2,91
-
(Air
=
1.0)
m)
Relative
density
0,95
g/cm3
at
20
°C
n)
o)
p)
q)
r)
s)
t)
Water
solubility
Partition
coefficient:
n-
octanol/water
Autoignition
temperature
Decomposition
temperature
Viscosity
Explosive
properties
Oxidizing
properties
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
no
data
available
9.2
10.
10.1
10.2
10.3
10.4
10.5
Other
safety
information
no
data
available
STABILITY
AND
REACTIVITY
Reactivity
no
data
available
Chemical
stability
no
data
available
Possibility
of
hazardous
reactions
no
data
available
Conditions
to
avoid
Heat,
flames
and
sparks.
Extremes
of
temperature
and
direct
sunlight.
Incompatible
materials
Acids,
Bases,
Halogens,
Strong
oxidizing
agents,
metal
salts
10.6
11.
11.1
Hazardous
decomposition
products
Other
decomposition
products
-
no
data
available
TOXICOLOGICAL
INFORMATION
Information
on
toxicological
effects
Acute
toxicity
no
data
available
Skin
corrosion/irritation
no
data
available
Serious
eye
damage/eye
irritation
no
data
available
Respiratory
or
skin
sensitization
no
data
available
Germ
cell
mutagenicity
Laboratory
experiments
have
shown
mutagenic
effects.
In
vivo
tests
showed
mutagenic
effects
Carcinogenicity
This
is
or
contains
a
component
that
has
been
reported
to
be
carcinogenic
based
on
its
IARC,
OSHA,
ACGIH,
NTP,
or
EPA
classification.
Human
carcinogen.
IARC:
1
-
Group
1:
Carcinogenic
to
humans
(Benzene-D6)
Reproductive
toxicity
no
data
available
Specific
target
organ
toxicity
-
single
exposure
no
data
available
Specific
target
organ
toxicity
-
repeated
exposure
no
data
available
Aspiration
hazard
May
be
fatal
if
swallowed
and
enters
airways.
Potential
health
effects
Inhalation
Ingestion
Skin
Eyes
May
be
harmful
if
inhaled.
Causes
respiratory
tract
irritation.
May
be
harmful
if
swallowed.
Aspiration
hazard
if
swallowed
-
can
enter
lungs
and
cause
damage.
May
be
harmful
if
absorbed
through
skin.
Causes
skin
irritation.
Causes
serious
eye
irritation.
Signs
and
Symptoms
of
Exposure
Nausea,
Dizziness,
Headache,
narcosis,
Inhalation
of
high
concentrations
of
benzene
may
have
an
initial
stimulatory
effect
on
the
central
nervous
system
characterized
by
exhilaration,
nervous
excitation
and/or
giddiness,
depression,
drowsiness,
or
fatigue.
The
victim
may
experience
tightness
in
the
chest,
breathlessness,
and
loss
of
consciousness.
Tremors,
convulsions,
and
death
due
to
respiratory
paralysis
or
circulatory
collapse
can
occur
in
a
few
minutes
to
several
hours
following
severe
exposures.
Aspiration
of
small
amounts
of
liquid
immediately
causes
pulmonary
edema
and
hemorrhage
of
pulmonary
tissue.
Direct
skin
contact
may
cause
erythema.
Repeated
or
prolonged
skin
contact
may
result
in
drying,
scaling
dermatitis,
or
development
of
secondary
skin
infections.
The
chief
target
organ
is
the
hematopoietic
system.
Bleeding
from
the
nose,
gums,
or
mucous
membranes
and
the
development
of
purpuric
spots,
pancytopenia,
leukopenia,
thrombocytopenia,
aplastic
anemia,
and
leukemia
may
occur
as
the
condition
progresses.
The
bone
marrow
may
appear
normal,
aplastic
or
hyperplastic,
and
may
not
correlate
with
peripheral
blood-forming
tissues.
The
onset
of
effects
of
prolonged
benzene
exposure
may
be
delayed
for
many
months
or
years
after
the
actual
exposure
has
ceased.,
Blood
disorders
Additional
Information
RTECS:
Not
available
12.
12.1
12.2
12.3
12.4
12.5
12.6
13.
13.1
14.
14.1
ECOLOGICAL
INFORMATION
Toxicity
no
data
available
Persistence
and
degradability
no
data
available
Bioaccumulative
potential
no
data
available
Mobility
in
soil
no
data
available
Results
of
PBT
and
vPvB
assessment
no
data
available
Other
adverse
effects
no
data
available
DISPOSAL
CONSIDERATIONS
Waste
treatment
methods
Product
Burn
in
a
chemical
incinerator
equipped
with
an
afterburner
and
scrubber
but
exert
extra
care
in
igniting
as
this
material
is
highly
flammable.
Offer
surplus
and
non-recyclable
solutions
to
a
licensed
disposal
company.
Contaminated
packaging
Dispose
of
as
unused
product.
TRANSPORT
INFORMATION
UN
number
14.2
14.3
14.4
14.5
14.6
15.
ADR/RID:
1114
UN
proper
shipping
name
ADR/RID:
BENZENE
IMDG:
BENZENE
IATA:
Benzene
Transport
hazard
class(es)
ADR/RID:
3
Packaging
group
ADR/RID:
II
Environmental
hazards
ADR/RID:
no
Special
precautions
for
user
no
data
available
REGULATORY
INFORMATION
IMDG:
1114
IMDG:
3
IMDG:
II
IMDG
Marine
pollutant:
no
IATA:
1114
IATA:
3
IATA:
II
IATA:
no
This
safety
datasheet
complies
with
the
requirements
of
Regulation
(EC)
No.
1907/2006.
15.1
15.2
Safety,
health
and
environmental
regulations/legislation
specific
for
the
substance
or
mixture
no
data
available
Chemical
Safety
Assessment
no
data
available
16.
OTHER
INFORMATION
Further
information
The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information this document is based on the resent state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Lookchem shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale.
|