1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol basic information |
product name: | 1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol |
synonyms: | 1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol;brivanib;tyrosine kinase inhibitor;(r)-1-(4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yloxy)propan-2-ol;2-propanol, 1-((4-((4-fluoro-2-methyl-1h-indol-5-yl)oxy)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)oxy)-, (2r)-;bms 540215;bms540215;unii-ddu33b674i |
cas: | 649735-46-6 |
mf: | c19h19fn4o3 |
mw: | 370.382 |
einecs: | |
product categories: | inhibitors |
mol file: | 649735-46-6.mol |
1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol chemical properties |
density | 1.42 |
safety information |
1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol usage and synthesis |
usage | brivanib is an atp-competitive inhibitor against human vegfr2 and fgfr with ic50 of 25 nm and 148 nm, respectively. |
1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol preparation products and raw materials |
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