chemical properties |
off-white to yellow to beige-grey crystalline |
chemical properties |
those engaged in the manufacture, formulation and application of this anthelmintic compound. incompatibilities: in general, keep away from strong oxidizers, moisture, strong acids, strong bases. this is a thiocyanate compound. violent reactions may occur upon contact with chlorates (potassium chlorate, sodium chlorate), nitrates, nitric acid; organic peroxides. |
uses |
reagent for solid-phase sequencing. |
uses |
anthelmintic |
general description |
odorless colorless crystals. melting point 132°c. |
reactivity profile |
1,4-phenylene diisothiocyanate reacts readily with amines [noller]. these reactions may generate significant amounts of heat . emits very toxic fumes of nitrogen oxides and sulfur oxides when heated to decomposition [epa, 1998]. |
health hazard |
1,4-phenylene diisothiocyanate is highly toxic if ingested. it is a central nervous system and gastrointestinal toxin in humans. |
fire hazard |
when heated to decomposition, 1,4-phenylene diisothiocyanate emits very toxic fumes of nitrogen oxides and sulfur oxides. |
safety profile |
poison by ingestion and intraperitoneal routes. human systemic effects by ingestion: hallucinations, nausea. when heated to decomposition it emits very toxic fumes of nox,cn,and sox.see also thiocyanates |
potential exposure |
those engaged in the manufacture, formulation and application of this anthelmintic compound. incompatibilities: in general, keep away from strong oxidizers, moisture, strong acids, strong bases. this is a thiocyanate compound. violent reactions may occur upon contact with chlorates (potassium chlorate, sodium chlorate), nitrates, nitric acid; organic peroxides. |
shipping |
un2811 toxic solids, organic, n.o.s., hazard class: 6.1; labels: 6.1—poisonous materials, technical name required. |
purification methods |
purify bitoscanate by recrystallisation from acoh, pet ether (b 40-60o), me2co or aqueous me2co. [van der kerk et al. recl trav chim pays-bas 74 1262 1955, leiber & slutkin j org chem 27 2214 1962, beilstein 13 iv 174.] |
incompatibilities |
incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. |