127-07-1 CH4N2O2 Hydroxyurea CAS NO.127-07-1

hydroxyurea basic information

product name:	hydroxyurea
synonyms:	biosupressin;carbamohydroxamicacid;carbamohydroxyamicacid;carbamoylhydroxylamine;carbamoyloxime;carbamylhydroxamate;hidrix;hu
cas:	127-07-1
mf:	ch4n2o2
mw:	76.05
einecs:	204-821-7
product categories:	miscellaneous biochemicals;pharmacetical;aliphatics;nucleotides and nucleosides;hydroxylamines;hydroxylamines (n-substituted);bases & related reagents;nitric oxide reagents;nucleotides;carbonyl compounds;organic building blocks;ureas;dna synthesis inhibitors;dna synthesis inhibitorscancer research;antitumor agents;apoptosis and cell cycle;dna metabolism;aids aided treatment;amines;hydrea;proteinmod;anti-cancer&immunity
mol file:	127-07-1.mol

hydroxyurea chemical properties

mp	135-140 °c
storage temp.	2-8°c
solubility	h2o: 50 mg/ml
form	powder
color	white
water solubility	soluble
merck	14,4848
brn	1741548
cas database reference	127-07-1(cas database reference)
epa substance registry system	urea, hydroxy-(127-07-1)

safety information

hazard codes	t,xn
risk statements	46-63-61-40
safety statements	53-36/37-45-36-22
ridadr	2811
wgk germany	3
rtecs	yt4900000
hazard note	toxic
packinggroup	iii
hazardous substances data	127-07-1(hazardous substances data)

msds information

hydroxyurea usage and synthesis

chemical properties	off-white crystalline solid
usage	an anti-neoplastic - inhibits ribonucleoside reductase and dna replication. a potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
usage	antineoplastic, inhibits ribonucleoside diphosphate reductase
general description	odorless or almost odorless white to off-white crystalline solid. tasteless.
air & water reactions	water soluble.
reactivity profile	an amide. amides/imides react with azo and diazo compounds to generate toxic gases. flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. amides are very weak bases (weaker than water). mixing amides with dehydrating agents such as p2o5 or socl2 generates the corresponding nitrile. the combustion of these compounds generates mixed oxides of nitrogen (nox).
fire hazard	flash point data for hydroxyurea are not available; however, hydroxyurea is probably combustible.

hydroxyurea preparation products and raw materials

preparation products	linuron
raw materials	urethane

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team.

we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market. we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!