4-Chlorotoluene CAS NO.106-43-4

production methods
the preparation method has the following kinds.
diazotization method
in reaction kettle to join the industrial hydrochloric acid and methyl aniline, kettle temperature dropped to 0 ℃, make of methyl aniline hydrochloride, stirring, adding sodium nitrite solution, make its diazotization reaction, temperature maintained at 0 ~ 5 ℃, time of about 30 min, diazotization reaction is completed, it added to the mixing of cuprous chloride solution, heats up to room temperature, stirring at room temperature is 2.5 ~ 3 h, then heated to a temperature of 60 ℃, the reactant gradually decomposed into nitrogen and chlorine toluene, then by steam distillation, the collection of chlorine toluene and a mixture of water, layering, organic layer by acid washing, washing with water, drying, distillation, collected 158 ~ 162 ℃ fraction of chlorotoluene, yield of about 70% ~ 79%.
direct chlorination process
after salt drying dehydration of toluene by measuring tank entered toluene chlorination reactor after measurement, measurement of chlorine by access to the bottom of the reactor, under a certain temperature, toluene and chlorine gas with ferric chloride as a catalyst for benzene chloride, generated a chlorine toluene chlorination liquid, the liquid chloride hurry with nitrogen gas and hydrogen chloride, then coarse steaming, for chlorine toluene and a mixture of chlorotoluene, its, adjacent than varies as the catalysts and reaction conditions, the general, adjacent ratio of 55:45.
of chlorotoluene and the separation of adjacent chlorotoluene available rectification method, molecular sieve adsorption method, distillation crystallization joint method, etc.distillation crystallization combined method, low energy consumption, the chlorine toluene and chlorine toluene content are higher, such as by falling film freezing crystallization, the toluene chloride content can reach more than 99%.