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7,8-Dihydroxyflavone manufacturer/supplier manufacturer/supplier CAS NO.38183-03-8

Min.Order Quantity:: 1 Gram

Purity:: 99%

Port:: shanghai

Payment Terms:: L/C,D/A,D/P,T/T,MoneyGram

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Product Details

Keywords

7,8-Dihydroxyflavone
7,8-Dihydroxyflavone manufacturer/supplier
38183-03-8

Quick Details

ProName: 7,8-Dihydroxyflavone manufacturer/s...
CasNo: 38183-03-8
Molecular Formula: C15H10O4
Appearance: white or off-white powder
Application: 7,8-Dihydroxyflavone CAS:38183-03-8...
DeliveryTime: in stock,shipment according to your re...
PackAge: aluminum oil bag
Port: shanghai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%
Storage: 0~20℃
Transportation: by express,by sea, by air
LimitNum: 1 Gram
Related Substances: ≤1.0%
Residue on Ignition: ≤0.1%
Heavy Metal: ≤20ppm
Valid Period: 2~3years
Brand: Royall
Grade Standard: Pharm grade
Chemical Name: 7,8-Dihydroxyflavone
Molecular Weight: 254.23700

Superiority

we can provide gmp validation service that complies with sfda, fda, who and eu empa.excellent registration team could help us easlily to register our products in different countries.if you and your customer are interested in some products or need cmo business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us.

besides, we could discuss the possible fdf distribution business. hope to get the chance to discuss deeply.

Details

hangzhou jinlan pharm-drugs technology co., limited is located in hangzhou, zhejiang province. neighboring ningbo port, shanghai port, hangzhou xiaoshan int’l airport and shanghai pudong int’l airport, the transportation and production environment are excellent.

we have established well market channels both domestically and overseas. now jinlan pharma is authorized by some chinese chemical factories as universal agency and international area agency. our products are exported to more than 100 countries and enjoy a well reputation, including europe, usa, south america, india, south-east asia and so on. such as canada, germany, spain, australia, russia, uae, estonia, indonesia, egypt, pakistan and so on. our machines with excellent quality, competitive price, good after-service, are highly welcomed by our customers. we are pleased to know you and hope to be good friend and cooperator with you for our products. i am sure you will be satisfied with us.

based on the philosophy of “human-orient, technical first, quality product and high efficiency, fact and innovation”, jinlan pharma highly welcome friends from all over the world to cooperate and get co-development.

basic info

chemical name

3-chloro-4-metdescription

7,8-dihydroxyflavone (7,8-dhf) is a naturally-occurring flavone found in godmania aesculifolia, tridax procumbens, and primula tree leaves. it has been found to act as a potent and selective small-molecule agonist of the trkb receptor (kd ≈ 320 nm), the main signaling receptor of brain-derived neurotrophic factor (bdnf). 7,8-dhf is both orally-bioavailable and able to penetrate the blood-brain-barrier.
7,8-dhf has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, alzheimer's disease, cognitive deficits in schizophrenia, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile x syndrome, and rett syndrome. 7,8-dhf also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents. in addition, 7,8-dhf possesses powerful antioxidant activity independent of its actions on the trkb receptor, and protects against glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity. it was also found to block methamphetamine-induced dopaminergic neurotoxicity, an effect which, in contrast to the preceding, was found to be trkb-dependent.

basic info

chemical name	7,8-dihydroxyflavone
synonyms	7,8-dihydroxy-2-phenylchromen-4-one;7,8-dihydroxyflavone hydrate;7,8-dihydroxy-2-phenyl-4h-chromen-4-one;7,8-dihydroxyflavone;
cas no.	38183-03-8
molecular formula	c15h10o4
molecular weight	254.23700
psa	70.67000
logp	2.87120

numbering system

mdl number

mfcd00006836

properties

density	1.443g/cm3
boiling point	494.4ºc at 760 mmhg
melting point	243-246ºc
flash point	193.5ºc
refractive index	1.698

safety info

rtecs	dj3004000
safety statements	24/25
hs code	2914400090
hazard declaration	h302
signal word	warning
symbol	ghs07

hoxybenzylamine hydrochloride

synonyms

(3-chloro-4-methoxyphenyl)methanamine hydrochloride;(3-chloro-4-methoxyphenyl)methanaminehydrochloride;3-chloro-4-methoxybenzylamine hydrochloride;

cas no.

41965-95-1

molecular formula

c8h11cl2no

molecular weight

208.08500

psa

35.25000

logp

3.30960

numbering system

mdl number

mfcd01211460

properties

appearance & physical state	white to yellow powder, crystals or crystalline powder and/or chunks
boiling point	263.5ºc at 760 mmhg
melting point	250-255ºc(lit.)
flash point	113.2ºc