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HENAN SUNLAKE ENTERPRISE CORPORATION7-Ethyl-10-hydroxycamptothecin//file1.lookchem.com/300w/synthetic/2022-01-22-12/4b2f0a6d-ffa4-4f4a-8a96-a66b531e67aa.png
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7-Ethyl-10-hydroxycamptothecin CAS NO.86639-52-3

Min.Order Quantity:
100 Gram
Purity:
99%
Port:
Any Chinese main ports
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • SN38
  • HIGH purity by own lab 86639-52-3
  • 10-dihydroxy-

Quick Details

  • ProName: 7-Ethyl-10-hydroxycamptothecin
  • CasNo: 86639-52-3
  • Molecular Formula: C22H20N2O5
  • Appearance: Light-Yellow Solid
  • Application: 150810-68-7 A metabolite of Irinote...
  • DeliveryTime: Within 7 working days since received y...
  • PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
  • Port: Any Chinese main ports
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: 2-8, cold storage, to avoid light stor...
  • Transportation: BY SEA /BY AIR /BY COURIER
  • LimitNum: 100 Gram
  • Heavy metal: NULL
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Certification: ISO/9001 Certificate

Superiority

7-ethyl-10-hydroxycamptothecin basic information
product name: 7-ethyl-10-hydroxycamptothecin
synonyms: camptothecin, 7-ethyl-10-hydroxy;4,11-diethyl-4,9-dihydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;7-ethyl-10-hydroxycamptothecin;7-ethyl-10-hydroxycamptothecine;7-ethyl-10-hydroxy-cpt;sn38;10-dihydroxy-;4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4,7-diethyl-1h-pyrano(3
cas: 86639-52-3
mf: c22h20n2o5
mw: 392.4
einecs:
product categories: pharmaceutical raw materials;miscellaneous natural products;antitumors for research and experimental use;biochemistry;natural plant extract;chiral reagents;intermediates & fine chemicals;metabolites & impurities;pharmaceuticals;natural anti-cancer medical materials and it's derivatives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;chiral reagents, metabolites & impurities, pharmaceuticals, intermediates & fine chemicals;inhibitors
mol file: 86639-52-3.mol
7-ethyl-10-hydroxycamptothecin structure
7-ethyl-10-hydroxycamptothecin chemical properties
mp 217 °c
refractive index 21.5 ° (c=0.2, thf)
storage temp. −20°c
cas database reference 86639-52-3(cas database reference)
safety information
hazard codes t
risk statements 25
safety statements 45
rtecs uq0491000
msds information
7-ethyl-10-hydroxycamptothecin usage and synthesis
chemical properties light-yellow solid
usage a metabolite of irinotecan, a dna topoisomerase inhibitor
biological activity active metabolite of cpt-11 that inhibits dna topoisomerase i (ic 50 values are 0.74 and 1.9 μ m in p388 and ehrlich cells respectively). inhibits dna and rna synthesis (ic 50 values are 0.077 and 1.3 μ m respectively) but does not affect protein synthesis. displays potent antitumor activity against a range of human tumor cell lines (ic 50 values are 3.3, 13, 19 and 22 nm for hct-116, bel-7402, hl60 and hela cells respectively).
7-ethyl-10-hydroxycamptothecin preparation products and raw materials
preparation products irinotecan

service we provide:

1. mixed container, we can mix different items in one container.

2. quality control, before shipment, free sample for test. after shipment, keep sample for 3 years

3. prompt shipment with professional documents

4. packing as your request, with photo before shipment

Details

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