USD $1.00-10.00 / Kilogram
USD $15.00-50.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $15.00-50.00 / Kilogram
USD $15.00-50.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $15.00-50.00 / Kilogram
USD $1.00-10.00 / Kilogram
USD $15.00-50.00 / Kilogram
7-ethyl-10-hydroxycamptothecin basic information |
product name: | 7-ethyl-10-hydroxycamptothecin |
synonyms: | camptothecin, 7-ethyl-10-hydroxy;4,11-diethyl-4,9-dihydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;7-ethyl-10-hydroxycamptothecin;7-ethyl-10-hydroxycamptothecine;7-ethyl-10-hydroxy-cpt;sn38;10-dihydroxy-;4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4,7-diethyl-1h-pyrano(3 |
cas: | 86639-52-3 |
mf: | c22h20n2o5 |
mw: | 392.4 |
einecs: | |
product categories: | pharmaceutical raw materials;miscellaneous natural products;antitumors for research and experimental use;biochemistry;natural plant extract;chiral reagents;intermediates & fine chemicals;metabolites & impurities;pharmaceuticals;natural anti-cancer medical materials and it's derivatives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;chiral reagents, metabolites & impurities, pharmaceuticals, intermediates & fine chemicals;inhibitors |
mol file: | 86639-52-3.mol |
7-ethyl-10-hydroxycamptothecin chemical properties |
mp | 217 °c |
refractive index | 21.5 ° (c=0.2, thf) |
storage temp. | −20°c |
cas database reference | 86639-52-3(cas database reference) |
7-ethyl-10-hydroxycamptothecin usage and synthesis |
chemical properties | light-yellow solid |
usage | a metabolite of irinotecan, a dna topoisomerase inhibitor |
biological activity | active metabolite of cpt-11 that inhibits dna topoisomerase i (ic 50 values are 0.74 and 1.9 μ m in p388 and ehrlich cells respectively). inhibits dna and rna synthesis (ic 50 values are 0.077 and 1.3 μ m respectively) but does not affect protein synthesis. displays potent antitumor activity against a range of human tumor cell lines (ic 50 values are 3.3, 13, 19 and 22 nm for hct-116, bel-7402, hl60 and hela cells respectively). |
7-ethyl-10-hydroxycamptothecin preparation products and raw materials |
preparation products | irinotecan |
service we provide:
1. mixed container, we can mix different items in one container.
2. quality control, before shipment, free sample for test. after shipment, keep sample for 3 years
3. prompt shipment with professional documents
4. packing as your request, with photo before shipment
we have clients throughout the world:
professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
our laboratoy
we have our own independent lab test center:
this makes sure that our technology support is reliable and authoritative.all of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.
our factory
high quality with competitive price:
we are manufacturer and can provide high quality products with factory price
package & shipment
fast and safe delivery:
parcels can be sent out within 24 hours after payment. tracking number is available
secure and discreet shipment. you have various choices of transportation methods