89-57-6 CAS NO.89-57-6

5-aminosalicylic acid basic information
product name: 5-aminosalicylic acid
synonyms: labotest-bb lt00134704;iflab-bb f1918-0003;benzoic acid, 5-amino-2-hydroxy-;m-aminosalicylic acid;mesalamine;mesalazine;2-hydroxy-5-aminobenzoic acid;3-carboxy-4-hydroxyaniline
cas: 89-57-6
mf: c7h7no3
mw: 153.14
einecs: 201-919-1
product categories: fine chemical & intermediates;aromatic carboxylic acids, amides, anilides, anhydrides & salts;carboxylic acids;phenyls & phenyl-het;organic acids;various metabolites and impurities;fendosal;intermediates & fine chemicals;metabolites & impurities;pharmaceuticals;carboxylic acids;phenyls & phenyl-het;aromatics;api;citanest;aromatics, metabolites & impurities, pharmaceuticals, intermediates & fine chemicals
mol file: 89-57-6.mol
5-aminosalicylic acid structure
5-aminosalicylic acid chemical properties
melting point 275-280 °c (dec.)(lit.)
fp 279-281°c
storage temp. 2-8°c
form tablets
color off-white to gray
water solubility <0.1 g/100 ml at 21 ºc
decomposition 279-281 ºc
merck 14,5904
brn 2090421
stability: stable. incompatible with acids, acid anhydrides, acid chlorides, chloroformates, strong oxidizing agents.
cas database reference 89-57-6(cas database reference)
nist chemistry reference mesalamine(89-57-6)
epa substance registry system benzoic acid, 5-amino-2-hydroxy-(89-57-6)
safety information
hazard codes xi
risk statements 36/37/38
safety statements 26-36-24/25
wgk germany 2
rtecs vo1400000
f 8-10-23
hazard note irritant
hazardclass irritant
hs code 29225000
hazardous substances data 89-57-6(hazardous substances data)
msds information
provider language
3-carboxy-4-hydroxyaniline english
sigmaaldrich english
acros english
alfa english
5-aminosalicylic acid usage and synthesis
chemical properties off-white crystals
usage the active metabolite of sulfasalazine. anti-inflammatory (gastrointestinal)
usage the active metabolite of sulfasalazine (s699084). anti-inflammatory (gastrointestinal).
usage anesthetic (local)
usage peroxidase substrate
usage for the treatment of active ulcerative proctitis.
general description odorless white to pinkish crystals or purplish-tan powder. aqueous solutions acidic (ph approximately 4.1 at 0.8 mg/l water) .
air & water reactions sensitive to moisture. water insoluble.
reactivity profile 5-aminosalicylic acid is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizers.
fire hazard flash point data for 5-aminosalicylic acid are not available; however, 5-aminosalicylic acid is probably combustible.
5-aminosalicylic acid preparation products and raw materials
raw materials sodium carbonate-->zinc-->water-->sodium dithionite-->methanesulfonyl chloride-->salicylic acid-->tyramine-->5-nitrosalicylic acid
preparation products benzoic acid, 2-[[1-amino-7-[[4-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sulfo-2-naphthalenyl]azo]-2-methoxyphenyl]azo]-8-hydroxy-3,6-disulfo-2-naphthalenyl]azo]-5-[[6-amino-5-[(3-carboxy-4-hydroxyphenyl)azo]-1-hydroxy-3-sul
tag:5-aminosalicylic acid(89-57-6) related product information
chrysamine g mordant yellow 12 2,6-dimethoxy-3-nitrobenzoic acid 2-hydroxy-3-methyl-5-[(4-sulfophenyl)azo]benzoic acid sodium salt methyl 2,6-dimethoxy-3-nitrobenzoate mordant orange 1 5-aminosalicylic acid altrenogest phosphoric acid acetic acid glycine 4-aminobenzoic acid chlorophosphonazo iii 3,5-dinitrosalicylic acid 4-aminosalicylic acid, 98+%,p-aminosalicylic acid,aminosalicylic acid,4-aminosalicylic acid acetylsalicylic acid salicylic acid folic acid
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