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Chemical Co.Ltd99% High Quality API-Letrozole CAS no:112809-51-5 with best price//file1.lookchem.com/cas/reactions/2021/05/26/6813913.png

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99% High Quality API-Letrozole CAS no:112809-51-5 with best price CAS NO.112809-51-5

FOB Price:
USD 1.00-1.00 /Metric Ton Get Latest Price
Min.Order Quantity:
1 Metric Ton
Purity:
99%min
Port:
Shanghai port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • 99% High Quality API-Letrozole CAS no:112809-51-5 with best price
  • Letrozole
  • CAS 112809-51-5

Quick Details

  • ProName: 99% High Quality API-Letrozole CAS no:...
  • CasNo: 112809-51-5
  • Molecular Formula: C17H11N5
  • Appearance: WhitePowder
  • Application: pharmaceutical intermediates
  • DeliveryTime: within 5-7 days after payment
  • PackAge: 25kg/ drum, or as your requirements
  • Port: Shanghai port
  • ProductionCapacity: 100 Metric Ton/Month
  • Purity: 99%min
  • Storage: regualr storage
  • Transportation: By air、ship and courier
  • LimitNum: 1 Metric Ton
  • Related Substances: undetected
  • Residue on Ignition: less than 0.05%
  • Heavy Metal: less than 0.02%
  • Valid Period: 3 years
  • EINECS: C17H11N5
  • Application: Pharm Intermediates
  • Appearance: WhitePowder
  • Molecular Weight: 285.3
  • Melting point: 181-183°C
  • Brand: zhishang
  • Product name: Letrozole
  • HPLC: available
  • NMR: available

Superiority

1.professional manufacturer
2.best price
3.fast delivery
4.prompt before and after sale service
5.quality guarantee
6.reliable and truthworthy supplier

Details

letrozole is an oral non-steroidal aromatase inhibitor for the treatment of hormonally-responsive breast cancer after surgery.

letrozole has been used for ovarian stimulation by fertility doctors since 2001 because it has fewer side-effects than clomiphene and less chance of multiple gestation. a study of 150 babies following treatment with letrozole or letrozole and gonadotropins presented at the american society of reproductive medicine 2005 conference found no difference in overall abnormalities but did find a significantly higher rate of locomotor and cardiac abnormalities among the group having taken letrozole compared to natural conception.a larger, follow-up study with 911 babies compared those born following treatment with letrozole to those born following treatment with clomiphene. that study also found no significant difference in the rate of overall abnormalities, but found that congenital cardiac anomalies was significantly higher in the clomiphene group compared to the letrozole group.

the anti-estrogen action of letrozole has been shown to be useful in pretreatment for termination of pregnancy, in combination with misoprostol. it can be used in place of mifepristone, which is expensive and unavailable in many countries.

letrozole is sometimes used as a treatment for gynecomastia, although it is probably most effective at this if caught in an early stage (such as in users of anabolic steroids).

some studies have shown that letrozole can be used to promote spermatogenesis in male patients suffering from nonobstructive azoospermia.

letrozole has also been shown to delay the fusing of the growth plates in mice.when used in combination with growth hormone, letrozole has been shown effective in one adolescent boy with a short stature.

letrozole has also been used to treat endometriosis.

tests

specifications

results

appearance

white or off-white crystaline powder

white

crystalline powder

solubility

soluble in chloroform;

soluble in ethanol when heated

conform

ldentification

(1)maximum absorption in wavelength of 240 nm

minimum absorption in wavelength of 215 nm

conform

conform

(2)infrared spectrum should be in accordance the dominant peak of contrast

in accordance with the dominant peak of contrast

melting points

182°c-184°c

182°c

related substances

≤0.5%

0.3%

single impurity

≤0.3%

0.2%

loss on drying

≤1.0%

0.8%

[assay]c17h11n5

(on anhydrous basis)

≥98.0%

99.2%

conclusion

conforms specifications of enterprise standard.


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