99%min Bendamustine Hydrochloride 3543-75-7 CAS NO.3543-75-7

Min.Order Quantity:: 10 Gram

Purity:: 99%min

Port:: ShangHai

Payment Terms:: T/T,MoneyGram

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Product Details

Keywords

99%min Bendamustine Hydrochloride
Bendamustine Hydrochloride Manufacturer
For Antitumor

Quick Details

ProName: 99%min Bendamustine Hydrochloride 3543...
CasNo: 3543-75-7
Molecular Formula: C16H22Cl3N3O2
Appearance: White Powder
Application: For Pharmaceutical Raw Materials
DeliveryTime: 2-4 days after confirmed your payments
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: ShangHai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%min
Storage: Dry and cool place
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

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advantages:

hubei xinrunde chemical co., ltd is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philosophy. we have flexible and untraceable payment terms. as a leading manufacture, our products have been exported to germany, norway, poland, finland, spain, uk, france, russia, usa, brazil, mexico, australia, japan, korea, thailand, indonesia, uruguay and many other countries.

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4 . warm after-sale service any of your question would be solved for the first as soon as possible.

Details

bendamustine hydrochloride basic information

product description indications the dose and medication pharmacological effects pharmacokinetics contraindications drug interactions adverse reactions and side effects

product name:	bendamustine hydrochloride
synonyms:	bendamustine hydrochloride;bendamustin hydrochloride;cytostasan;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryric acid hydrochloride;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid hydrochloride;1-methyl-5-bis(2-chloroethyl)amino-2-benzimidazolinebutryricacihydrochlor;gamma(1-methyl-5-bis(beta-chloraethyl)aminobenzimidazoyl-2)buttersaeurehydro;bendamustine hcl
cas:	3543-75-7
mf:	c16h22cl3n3o2
mw:	394.72
einecs:	1592732-453-0
product categories:	api intermediates;intermediates & fine chemicals;pharmaceuticals;api;amines;heterocycles;ribomustin, treanda, sdx-105
mol file:	3543-75-7.mol

bendamustine hydrochloride chemical properties

melting point	149-151°c
storage temp.	desiccate at rt
solubility	h2o: >30mg/ml
color	off-white
merck	14,1034
inchikey	zhskuozolhmkea-uhfffaoysa-n
cas database reference	3543-75-7(cas database reference)

safety information

hazard codes	t,xn
risk statements	60-61-22-40
safety statements	36-37
ridadr	un 2811 6.1 / pgiii
rtecs	de1590000
hazardclass	6.1
packinggroup	iii
hs code	29339900

bendamustine hydrochloride usage and synthesis

product description

bendamustine hydrochloride was first successfully developed in the early 1860s by the ozegowski and his colleagues in the “microbiology experiment association (jena in germany)”. the original purpose of developing it is intended to make a kind of alkylated chloremethine (a non-effective alkylating agent) be connected to a purine and amino acids. compared with the chlorambucil, the main advantage of the newly synthesized compound is its water solubility. it was then widely applied. however, it is not until the end of the cold war before the drug had been applied in europe to clinical studies in either a number of single medication or in combination with other drugs for treating various kinds of blood malignancies and non-hodgkin's lymphoma, multiple myeloma, cll and breast cancer and some other solid tumors. the efficacy is very impressive. the drug had significantly reduced the recurrence rate and death rate with small adverse reactions and good security. so far, the clinical protocols of both monotherapy and combination therapy of bendamustine hydrochloride has been designated as either first-or second-line treatment option for treating various kinds of hematological malignancies by europe and america clinical guidelines.
from 1971 to 1992, bendamustine was sold by the jena pharmaceutical companies in the trade name of “cytostasan”. from 1993, the cell growth inhibitor entered into market with the trade name “ribomustine” mediated by ribosepharm company.
in 2003, the bendamustine hydrochloride product developed by german ribosepharm company entered into market in germany with the trade name "ribomustin".
in 2008, the bendamustine hydrochloride injection product developed by the united states cephalon company entered into market in united states under the trade name “treanda” which is used for the treatment of the relapsed and refractory b-cell non-hodgkin’s lymphoma which is failed be to be treated rituximab monotherapy.

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