99%min Raltegravir 518048-05-0 CAS NO.518048-05-0

Min.Order Quantity:: 10 Gram

Purity:: 99%min

Port:: ShangHai

Payment Terms:: T/T,

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Product Details

Keywords

99%min Raltegravir
Raltegravir Manufacturer
For Anti-AIDS

Quick Details

ProName: 99%min Raltegravir 518048-05-0
CasNo: 518048-05-0
Molecular Formula: C20H21FN6O5
Appearance: White Powder
Application: For Pharmaceutical Raw Materials
DeliveryTime: 2-4 days after confirmed your payments
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: ShangHai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%min
Storage: Dry and cool place
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

Superiority

advantages:

hubei xinrunde chemical co., ltd is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philosophy. we have flexible and untraceable payment terms. as a leading manufacture, our products have been exported to germany, norway, poland, finland, spain, uk, france, russia, usa, brazil, mexico, australia, japan, korea, thailand, indonesia, uruguay and many other countries.

1. quality.every batch of steroid powders have tobetested by our qc(quality control) before they are allowed to sell.

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4 . warm after-sale service any of your question would be solved for the first as soon as possible.

Details

raltegravir basic information

product features

product name:	raltegravir
synonyms:	raltegravir;n-((4-fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)amino)ethyl)-6-oxo-4-pyrimidinecarboxamide;n-(2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1,3,4-oxadiazole-2-carboxamide;n-(2-(4-(4-fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)p;raltegravir(r&d);raltegravir(free base);n-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-(2-methyl-1,3,4-oxadiazole-5-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide;n-((4-fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)am
cas:	518048-05-0
mf:	c20h21fn6o5
mw:	444.42
einecs:	1312995-182-4
product categories:	api;isentress;inhibitors
mol file:	518048-05-0.mol

raltegravir usage and synthesis

product features

merck's raltegravir is the first hiv integrase strand transfer inhibitor (referred to as an integrase inhibitor). it is also known as mk-0518, which can treat human immunodeficiency virus (hiv)-1 infection combining with other antiretroviral (arv) drugs. it slows hiv-1 infection by inhibiting the necessary hiv integrase for viral replication. when raltegravir combines with other anti-hiv drugs, it can reduce the amount of hiv in the blood, while it can increase the number of so-called cd4+ t cells that belong to white blood cells. it helps against other infections. the interaction between raltegravir and ritonavir, efavirenz, tipranavir and tenofovir indicates that there is no drug cross-resistance, and there is a synergistic effect with a variety of drugs. the most common adverse reactions are diarrhea, nausea, headache. in addition, blood tests show that the muscle enzymes abnormally increased in some of patients who taked this drug.
the above information is edited by the chemicalbook of kui ming.

uses

raltegravir (mk-0518, isentress) is a potent integrase (in) inhibitor for wt and s217q pfv in with ic50 of 90 nm and 40 nm, respectively.

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