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Wuhan Recedar Biotechnology Co., Ltd99% raw powder Vildagliptin//www.lookchem.com/300w//2010/0620/274901-16-5.jpg
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99% raw powder Vildagliptin CAS NO.274901-16-5

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FOB Price:
USD 1.00-1.00 /Kilogram Get Latest Price
Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
Shanghai,Guangzhou
Payment Terms:
L/C,D/P,T/T,Western Union,MoneyGram,Other

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Product Details

Keywords

  • Vildagliptin
  • Vildagliptin powder
  • Vildagliptin factory

Quick Details

  • ProName: 99% raw powder Vildagliptin
  • CasNo: 274901-16-5
  • Molecular Formula: 274901-16-5
  • Appearance: white or off-white Solid
  • Application: Labelled Vildagliptin. It is a new ora...
  • DeliveryTime: within a week
  • PackAge: carton drum
  • Port: Shanghai,Guangzhou
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99%
  • Storage: Stored in a well-closed container away...
  • Transportation: by sea/air/express
  • LimitNum: 1 Kilogram
  • Related Substances: Vildagliptin
  • Residue on Ignition: 99%
  • Heavy Metal: 10ppm
  • Valid Period: 24 months

Superiority


99% raw powder Vildagliptin

Basic info

Product Name: Vildagliptin
Synonyms: pharma API Vildagliptin;Vildagliptin API;2-Pyrrolidinecarbonitrile,1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)aMino]acetyl]-, (2S)-;Vildagliptin (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile;1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine;Vildaliptin;Vildagliptin (NVP-LAF 237);Vildagliptin, 97%, DPP-4 inhibitor
CAS: 274901-16-5
MF: C16H15F6N5O H3O4P H2O
MW: 303.4
EINECS: 630-410-0
Melting point 153-155 C
alpha -78.3° (c = 9.73 in methanol)
Boiling point 531.3±50.0 °C(Predicted)
density 1.27
Fp 275.1℃
HS Code 29339900
Uses The major metabolite of Vildagliptin
Uses Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.

Vildagliptin, a DPP-4 inhibitor, was launched for the oral treatment of type 2 diabetes. Vildagliptin is the second DPP-4 inhibitor to reach the market behind sitagliptin, which was introduced in 2006. DPP-4 inhibitors act by slowing the inactivation of incretins, which are endogenous peptides involved in the physiologic regulation of glucose homeostasis. When blood glucose concentrations are normal or elevated, GLP-1 and GIP increase the synthesis and release of insulin from pancreatic βcells via intracellular signaling pathways involving cAMP. GLP-1 also lowers glucagon secretion from pancreatic α cells, which leads to reduced hepatic glucose production. However, although GLP-1 and GIP effectively lower blood glucose, they are short-lived as a result of rapid inactivation by the ubiquitous serine protease DPP-4. By inhibiting DPP-4, vildagliptin increases the concentration and duration of active incretin levels, which in turn results in increased insulin release and decreased glucagon levels in a glucose-dependent manner. Both vildagliptin and sitagliptin are potent, competitive, reversible inhibitors of DPP- 4 (IC50=3.5 and 18 nM, respectively), and they both show slow, tight-binding inhibition kinetics.

Packing and storage

Packing:25kg carton drum,double-layer plastic bags inside

Sttorage:Sealed in cool and dry place, keep away from strong light and heat.

Shelf life: 24 months when properly stored.

COA and other ceitificates will be sent under request.

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Details

Company Profile

Wuhan Recedar Biotechnology Co., Ltd, located in Donghu high-tech development zone, China, is one of the leading manufacture of natural color and plant extract. We are engaged in research, development, producing and marketing. With our strict quality-control system and years of good reputation, our products are widely used in pharmaceuticals, cosmetics, food, nutrients etc.

Currently,Recedarbio has four production departments (PDs), and more than 200 employees. The company has its own R&D team, complete testing equipments, qualified enviormental protection system in accordance with the national standard, and also has clean production environment.

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