ABT-199 Intermediates CAS No. 1228779-96-1 Venetoclax intermediate CAS NO.1228779-96-1

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vemurafenib & intermediate

no.

product name

cas no.

1.

vemurafenib, plx4032

1029872-54-5

2.

5-(4-chlorophenyl)-1h-pyrrolo[2,3-b]pyridine

918516-27-5

3.

2,6-difluoro-3-(propylsulfonamido)benzoic acid

1103234-56-5

4.

plx-4720, n-(3-(5-chloro-1h-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918505-84-7

5.

n-(3-(5-bromo-1h-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

918504-27-5

indacaterol& intermediate

1.

indacaterol

312753-06-3

2.

(r)-8-(benzyloxy)-5-(oxiran-2-yl)quinolin-2(1h)-one

173140-90-4

3.

8-(benzyloxy)-5-(2-bromoacetyl)quinolin-2(1h)-one

100331-89-3

4.

5,6-diethyl-2,3-dihydro-1h-inden-2-amine hydrochloride

312753-53-0

lurasidone& intermediate

1.

bicyclo[2.2.1]hep-tane-2,3-exo- dicarboximide

14805-29-9

2.

(1r,2r)-1,2-cyclohexanedimethanol

65376-05-8

3.

(1r,2r)-trans-1,2 bis (methan sulfonyl-oxymethyl) cyclohexane

186204-35-3

cabozantinib& tivozanib intermediate

1.

4-chloro-6,7-dimethoxyquinoline

35654-56-9

2.

4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline

190728-25-7

3.

1-((4-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid

849217-48-7

4.

phenyl(2-chloro-4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamate

ivabradine & intermediates

1.

(1s)-4,5-dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

866783-13-3

2.

3-(3-chloropropyl)-7,8-dimethoxy-1h-3-benzazepin-2(3h)-one

85175-59-3

3.

7,8-dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2h-3-benzaze pin-2-one

148870-57-9

4.

8-demethyl ivabradine

304464-97-9

edoxaban& intermediates

1.

(1s)-cyclohex-3-ene-1-carboxylic acid

5708-19-0

2.

(1r)-cyclohex-3-ene-1-carboxylic acid

5709-98-9

3.

ethyl(1s,3r,4r)-3-((tert-butoxycarbonyl)amino)-4-hydroxycyclohexane-1-carboxylate

365997-33-7

4.

tert-butyl((1r,2s,5s)-2-amino-5-(dimethylcarbamoyl)cyclohexyl)carbamate

1210348-34-7

5.

5-methyl-6,7-dihydro-4h-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid

720720-96-7

6.

n-(5-chloro-pyridin-2-yl)-oxalamic acid ethyl ester

349125-08-2

ticagrelor inter. isomers

1.

(1s,2r)-2-(3,4-difluorophenyl)cyclopropan-1-amine

1345413-20-8

2.

(1r,2r)-2-(3,4-difluorophenyl)cyclopropan-1-amine

3.

(1s,2s)-2-(3,4-difluorophenyl)cyclopropan-1-amine

4.

2-(((3as,4r,6s,6ar)-6-amino-2,2-dimethyltetrahydro-4h-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol

other api products

1.

tigecycline 99.9% gmp or 99.8%

220620-09-7

2.

abiraterone acetate 99.5%

154229-18-2

3.

daunorubicin hydrochloride 98.9%

23541-50-6

4.

galanthamine hydrobromide 99.7%

1953-04-4

5.

epalrestat, 99.5%

82159-09-9

6.

ceritinib

1032900-25-6

7.

oxiracetam 99.7%

62613-82-5

fine chemical product

1.

n-benzylhydroxylamine hydrochloride

29601-98-7

2.

2-aminoindan hydrochloride

2338-18-3

3.

d(-)-ribose

50-69-1

4.

4-hexylbenzoic acid

21643-38-9

5.

4-cyanophenyl 4-hexylbenzoate

50793-85-6

6.

2-chloro-5-(methoxycarbonyl)benzoic

651058-97-8

in development process for the intermediates of abt-199, venetoclax

1.

abt-199, venetoclax

1257044-40-8

2.

4-fluoro-3-nitrobenzenesulfonamide

406233-31-6

3.

3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)benzenesulfonamide

1228779-96-1

4.

1h-pyrrolo[2,3-b]pyridin-5-ol

98549-88-3

5.

ethyl2-((1h-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1630101-74-4

6.

methyl 2-((1h-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate

1235865-75-4

7.

3,3-dimethylcyclohexanone

2979-19-3

8.

(4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol

1228837-05-5

9.

1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazine

1228780-72-0

10.

tert-butyl4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate

1228780-71-9

11.

2-((1h-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid

1235865-77-6

cinchona alkaloids products list

quinine& derivatives

no.

product name

cas no.

1.

quinine, (r)-(6-methoxyquinolin-4-yl)((1s,2s,4s,5r)-5-vinylquinuclidin-2-yl)methanol

130-95-0

2.

9-amino-(9-deoxy)epi-quinine trihydrochloride

168960-95-0

dihydroquinine& derivatives

1.

dihydroquinine (r)-((1s,2s,4s,5r)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

522-66-7

2.

9-amino-(9-deoxy)epi-dihydroquinine trihydrochloride

931098-91-8

3

(dhq)2pyr;hydroquinine 2,5-diphenyl-4,6-pyrimidinediyl diether

149820-65-5

quinidine & derivatives

1.

quinidine;(s)-(6-methoxyquinolin-4-yl)((1s,2r,4s,5r)-5-vinylquinuclidin-2-yl)methanol

56-54-2

2.

9-amino-(9-deoxy)epi- quinidine trihydrochloride

1391506-12-9

dihydroquinidine& derivatives

1.

dihydroquinidine;(s)-((1s,2r,4s,5r)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

1435-55-8

2.

9-amino-(9-deoxy)epi- dihydroquinidinetrihydrochloride

931098-92-9

3

(dhqd)2pyr; hydroquinidine-2,5-diphenyl-4,6-pyrimidinediyl diether

149725-81-5

cinchonine& derivatives

1.

cinchonine ;(s)-quinolin-4-yl((1s,2r,4s,5r)-5-vinylquinuclidin-2-yl)methanol

118-10-5

2.

9-amino-(9-deoxy)epi-cinchonine trihydrochloride

168960-96-1

dihydrocinchonine& derivatives

1.

dihydrocinchonine ;(s)-((1s,2r,4s,5r)-5-ethylquinuclidin-2-yl)(quinolin-4-yl)methanol

485-65-4

2.

9-amino-(9-deoxy)epi- dihydrocinchonine trihydrochloride

354532-49-3

cinchonidine& derivatives

1.

cinchonidine;(r)-(6-methoxyquinolin-4-yl)((1s,2s,4s,5r)-5-vinylquinuclidin-2-yl)methanol

485-71-2

2.

9-amino-(9-deoxy)epi- cinchonidine trihydrochloride

850409-61-9

dihydrocinchonidine & derivatives

1.

dihydrocinchonidine;

(r)-((1s,2s,4s,5r)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methanol

485-64-3

2.

9-amino-(9-deoxy)epi-dihydrocinchonidinetrihydrochloride