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Henan Tianfu Chemical Co., Ltd.Amlodipine besilate 111470-99-6//file1.lookchem.com/cas/reactions/2021/05/26/8378713.png
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Amlodipine besilate 111470-99-6 CAS NO.111470-99-6

Min.Order Quantity:
1 Kilogram
Purity:
99% min
Port:
SHANGHAI,PORT
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

  • 111470-99-6
  • Amlodipine besilate
  • Amlodipine besilate

Quick Details

  • ProName: Amlodipine besilate 111470-99-6
  • CasNo: 111470-99-6
  • Molecular Formula: C26H31ClN2O8S
  • Appearance: White Crystalline Solid
  • Application: For Organic Synthesis use
  • DeliveryTime: Prompt
  • PackAge: 25kg plastic drum
  • Port: SHANGHAI,PORT
  • ProductionCapacity: 10 Metric Ton/Month
  • Purity: 99% min
  • Storage: room temperature
  • Transportation: AS PEE MSDS
  • LimitNum: 1 Kilogram
  • Heavy metal: N/M
  • Grade: Industrial Grade,Food Grade,Pharma Gra...
  • Transporttation: N/M

Superiority

amlodipine besilate basic information
product name: amlodipine besilate
synonyms: 2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate;amlodipine benzenesulfonate;amlodipine besilate;amlodipine besylate;norvasc;3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,;4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
cas: 111470-99-6
mf: c26h31cln2o8s
mw: 567.05
einecs:
product categories: active pharmaceutical ingredients;dihydropyridine class chemicals;intermediates & fine chemicals;pharmaceuticals;amlodipine;aromatics;dihydropyridine;heterocycles;benicar;azd929
mol file: 111470-99-6.mol
amlodipine besilate structure

Details

amlodipine besilate chemical properties
mp 199-201°c
storage temp. store at rt
solubility dmso: 20 mg/ml
form solid
color white
cas database reference 111470-99-6(cas database reference)
safety information
hazard codes xn
risk statements 22-36/37/38-20/21/22
safety statements 26-36
wgk germany 3
rtecs us7967700
hazardous substances data 111470-99-6(hazardous substances data)
amlodipine besilate usage and synthesis
chemical properties white crystalline solid
usage a dihydropyridine calcium channel blocker. used as an antianginal and antihypertensive
usage angiotensin ii inhibitor prodrug, antihypertensive
usage amlodipine besylate is a l-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. amlodipine also inhibits growth of human epidermoid carcinoma a431 cells and has antireproductive effects in male rats.
biological activity l-type calcium channel blocker that displays antihypertensive properties. inhibits ca 2+ -induced contractions in depolarized rat aorta (ic 50 = 1.9 nm) and displays vasoprotective effects in cardiovascular disease. inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma a431 cells (ic 50 = 25 μ m).

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