brinzolamide is acarbonic anhydrase inhibitor used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
systematic (iupac) name | |
---|---|
(5r)-5-ethylamino-3-(3-methoxypropyl)- 2,2-dioxo-2λ6,9-dithia- 3-azabicyclo[4.3.0]nona-7,10-diene- 8-sulfonamide |
|
clinical data | |
trade names | azopt |
ahfs/drugs.com | monograph |
medlineplus | a601233 |
licence data | ema:link, us fda:link |
pregnancy cat. | c (us) |
legal status | -only (us) |
routes | ophthalmic |
pharmacokinetic data | |
bioavailability | absorbed systemically, but below detectable levels (less than 10 ng/ml) |
protein binding | ~60% |
half-life | 111 days |
excretion | renal (60%) |
identifiers | |
cas number | 138890-62-7 |
atc code | s01ec04 |
pubchem | cid 68844 |
drugbank | db01194 |
chemspider | 62077 |
unii | 9451z89515 |
kegg | d00652 |
chebi | chebi:3176 |
chembl | chembl220491 |
chemical data | |
formula | c12h21n3o5s3 |
mol. mass | 383.51 g/mol |