USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $5.00-10.00 / Gram
USD $3.00-10.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $3.00-10.00 / Kilogram
USD $11,000.00-12,000.00 / Metric Ton
USD $11,000.00-12,000.00 / Metric Ton
english name:rivastigmine tartrate
molecular formula : c18h28n2o8
molecular weight : 400.4235
cas: 129101-54-8
synonyms: sdz-ena 713;ena 713;ena-713;rivastigmine hydrogentartrate;unii-9iy2357jpe;carbamic acid, ethylmethyl-, 3-((1s)-1-(dimethylamino)ethyl)phenyl ester, (2r,3r)-2,3-dihydroxybutanedioate (1:1);carbamic acid, ethylmethyl-, 3-(1-(dimethylamino)ethyl)phenyl ester, (s)-, (r-(r*,r*))-2,3-dihydroxybutanedioate (1:1);rivastigmine hydrogen tartrate;3-[(1s)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (1:1);3-[(1s)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate 2,3-dihydroxybutanedioate (salt);rivastigimine tartrate;
introduction:
rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the alzheimer's type and dementia due to parkinson's disease. the drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. the drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.
specification
item |
requirements |
test results |
appearance |
white or off-white powder |
white powder |
identification |
nmr,ms |
complies |
water |
≤0.50% |
0.4% |
melting point |
121℃~126℃ |
122.0℃~124.1℃ |
specific rotation |
+4.0°~+6.0° |
+5.9° |
related substances(hplc) |
conformed |
|
(s)-3-1(-dimethylamino)ethyl-phenol |
≤0.30% |
0.2% |
any other individual impurity: |
≤0.50% |
0.31% |
total impurity |
≤1.0% |
0.8% |
residues on ignition |
≤0.1% |
0.05% |
residual solvent |
ethanol≤0.5% acetonitrile≤0.041% dichloromethane≤0.06% ethyl acetate≤0.5% |
nd nd nd nd 0.023% |
heavy metals |
≤10ppm |
<10ppm |
purity |
≥99.0% |
99. 9% |
conclusion |
meets the requirements |
application
use rivastigmine as directed by your doctor. check the label on the medicine for exact dosing instructions.
kono chem co.,ltd is a leading producer of standardized herbal extracts, natural active ingredients and apis for pharmaceutical, health food and cosmetic industries.
the botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by pioneer. they include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
with our phytopharmaceutical background and knowledge through experience, pioneer can also provide a wide range of analytical services and reference substances to our clients. in addition, we also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: sam-e tosylate disulfate; sam-e 1,4-butanedisulfonate; polycytidylic acid; polyinosinic acid; adenosine triphosphate disodium; and cytidine triphosphate disodium; these items are our strongest advantage in china. meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.
recently, kono chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. as a gmp standardized manufacturer, our products can meet or even exceed the standards of cp2010, usp32, bp2005 and ep4. presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as usa, eu, south america and southeast asia. there are experienced technicians working for our institutes now, all of them are skilled. pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.
email :sales7@konochemical.com