USD $8.00-10.00 / Metric Ton
USD $8.00-50.00 / Metric Ton
USD $2.30-10.00 / Metric Ton
USD $2.00-5.00 / Metric Ton
USD $1.00-8.00 / Metric Ton
USD $1.00-3.00 / Metric Ton
USD $35.00-69.00 / Metric Ton
colistin basic information |
product name: | colistin |
synonyms: | colistin;colimycin;colisticina;colomycin;coly-mycin;colymysins;kangdisu;kolimitsin |
cas: | 1066-17-7 |
mf: | c52h98n16o13 |
mw: | 1155.43 |
einecs: | 213-907-3 |
product categories: | |
mol file: | 1066-17-7.mol |
colistin chemical properties |
safety information |
ridadr | 3249 |
hazardclass | 6.1(b) |
packinggroup | iii |
colistin usage and synthesis |
usage | polymyxin e (colistin) is a complex of closely related cyclic peptides e1 and e2, with additional minor analogues. polymyxin e is produced by bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. head-to-tail coupling of lysine completes the macrocycle. balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. polymyxin e is a broad spectrum antibiotic active against gram negative bacteria. the mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect. |